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- Table of Contents
Prohibitin Antibodies
AND PHB ELISA kits, Prohibitin Proteins
Many biological assays use antibodies to detect Prohibitin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Prohibitin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Prohibitin antibodies...
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PHB Infographic by Boster Bio
All PHB Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # PA1932
100 μg/vial
Cat # PA1932
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01178
100 μl
Cat # M01178
100 μl
Human, Mouse, Rat
ELISA, IF, IHC, ICC, WB
$370
Cat # A01178-1
100 μg/vial
Cat # A01178-1
100 μg/vial
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M01178-1
20μL, 40μL, 100μL, 200μL
Cat # M01178-1
20μL, 40μL, 100μL, 200μL
PHB Overview
Facts about Prohibitin.
Prohibitin (PHB)
Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation.
As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging.
Gene Information
| Human | |
|---|---|
| Gene Name: | PHB |
| Uniprot: | P35232 |
| Entrez: | 5245 |
Family
| Belongs to: |
|---|
| prohibitin family |
Alternative Names
PHB; PHB1; Prohibitin
Molecular Weight
Mass (kDA):
29.804 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q21.33 |
| Sequence: | 17; NC_000017.11 (49404048..49414905, complement) |
Tissue Specificity
Widely expressed in different tissues.
Subcellular Localizations
Mitochondrion inner membrane. Nucleus.
Diseases
- Malignant Neoplasms
- Neoplasms
- Tissue Adhesions
- Inflammation
- Polyps
- Headache
- Carcinoma
- Epilepsy
- Cell Transformation, Neoplastic
- Agitation
- Malignant Neoplasm Of Breast
- Physiological Stress
Interacting Proteins
- LONRF3
- TNFRSF19
- Tnfrsf19
- TP53
- XPO1
Pathways
- Fermentation
- Cell Growth
- Regeneration
- Transport
- Cell Proliferation
- Localization
- Cell Cycle
- Nitrogen Fixation
- Secretion
- Pathogenesis
- Translation
- Cell Division
- Rna Interference
PTMs
- Nitration
- Oxidation
- Phosphorylation
- Cleavage
- Reduction
- Hydroxylation
- Carboxylation
- Decarboxylation
- Prenylation
Research Areas
- Cell Cycle and Replication
- Core ESC-Like Genes
- Ovarian Carcinoma Cell Markers
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PHB
bosterbio.com/bosterbio-gene-info-cards/PHB
References
PMID: 1540973 by Sato T., et al. The human prohibitin gene located on chromosome 17q21 is mutated in sporadic breast cancer.
PMID: 8244394 by Sato T., et al. The human prohibitin (PHB) gene family and its somatic mutations in human tumors.
1 Publications of Boster Prohibitin Antibodies & ELISA Kits
- PubMed ID: 18763282, Positional and expressive alteration of prohibitin during the induced differenti...
*More publications can be found for each product on its corresponding product page