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Pro-opiomelanocortin Antibodies
AND POMC ELISA kits, Pro-opiomelanocortin Proteins
Many biological assays use antibodies to detect Pro-opiomelanocortin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Pro-opiomelanocortin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Pro-opiomelanocortin antibodies...
Designing an IHC experiment for Pro-opiomelanocortin? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the POMC IHC GuidePOMC Infographic by Boster Bio
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POMC Overview
Facts about Pro-opiomelanocortin.
Pro-opiomelanocortin (POMC)
Corticotropin: Stimulates the adrenal glands to release cortisol. .
Gene Information
| Human | |
|---|---|
| Gene Name: | POMC |
| Uniprot: | P01189 |
| Entrez: | 5443 |
Family
| Belongs to: |
|---|
| POMC family |
Alternative Names
ACTH; adrenocorticotropic hormone; adrenocorticotropin; alpha-melanocyte-stimulating hormone; alpha-MSH; beta-endorphin; beta-LPH; beta-melanocyte-stimulating hormone; beta-MSH; CLIP; corticotropin-like intermediary peptide; corticotropin-lipotropin; gamma-LPH; gamma-MSH; lipotropin beta; lipotropin gamma; LPH; melanotropin alpha; melanotropin beta; melanotropin gamma; met-enkephalin; MSH; NPP; POC; POMC; pro-ACTH-endorphin; proopiomelanocortin preproprotein; proopiomelanocortin; pro-opiomelanocortin
Molecular Weight
Mass (kDA):
29.424 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2p23.3 |
| Sequence: | 2; NC_000002.12 (25160853..25168851, complement) |
Tissue Specificity
ACTH and MSH are produced by the pituitary gland.
Subcellular Localizations
Secreted. Melanocyte-stimulating hormone alpha and beta-endorphin are stored in separate granules in hypothalamic POMC neurons, suggesting that secretion may be under the control of different regulatory mechanisms.
Diseases
- Pituitary Diseases
- Obesity
- Neoplasms
- Pituitary Neoplasms
- Nervousness
- Hyperphagia
- Adenoma
- Physiological Stress
- Cushing Syndrome
- Diabetes Mellitus
- Inflammation
- Pituitary-dependent Cushing's Disease
Interacting Proteins
- HSF2BP
Pathways
- Secretion
- Energy Homeostasis
- Localization
- Pigmentation
- Secretory Pathway
- Feeding Behavior
- Lactation
- Pathogenesis
- Hormone Secretion
- Transport
- Translation
- Regulated Secretory Pathway
- Cell Proliferation
PTMs
- Cleavage
- Phosphorylation
- Acetylation
- Glycosylation
- Amidation
- Methylation
- Oxidation
- Deacetylation
- Sulphation
- Biotinylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/POMC
bosterbio.com/bosterbio-gene-info-cards/POMC
References
PMID: 6274691 by Takahashi H., et al. Isolation and structural organization of the human corticotropin- beta-lipotropin precursor gene.
PMID: 6299668 by Whitfeld P.L., et al. The human pro-opiomelanocortin gene: organization, sequence, and interspersion with repetitive DNA.
2 Publications of Boster Pro-opiomelanocortin Antibodies & ELISA Kits
- PubMed ID: 16355451, Chen L, Wang H, Zhao Z, Zhang Y, Huang G. Am J Chin Med. 2005;33(6):945-55. Effe...
- PubMed ID: 25624795, Huo J, Liu J, Wang J, Zhang Y, Wang C, Yang Y, Sun W, Xu S. Neural Regen Res. 20...
*More publications can be found for each product on its corresponding product page