PPP1R14D Antibodies

AND PPP1R14D ELISA kits, PPP1R14D Proteins

Many biological assays use antibodies to detect PPP1R14D, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PPP1R14D in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PPP1R14D antibodies...

We validate the specificity of these antibodies to PPP1R14D by testing them on tissues known to express PPP1R14D positively and negatively. Browse below to find the PPP1R14D antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for PPP1R14D? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the PPP1R14D IHC Guide

PPP1R14D Infographic by Boster Bio

All PPP1R14D Products

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Product

Figures

Specificity

Applications

Price

Anti-PPP1R14D/Gbpi 1 Antibody

Western Blot analysis of various cells using PPP1R14D Polyclonal Antibody

Western blot analysis of lysates from HeLa, HepG2, and COLO cells, using PPP1R14D Antibody

Immunohistochemical analysis of paraffin-embedded human tonsil

Human, Mouse, Rat

ELISA, IF, IHC, WB

$399
Cat # A14433
100μl

PPP1R14D (NM_017726) Human Over-expression Lysate

Human

$628
Cat # LS054866
20 µg, 100 µg

PPP1R14D (NM_017726) Human Recombinant Protein

Coomassie blue staining of purified PPP1R14D protein

$1249
Cat # PROTQ9NXH3
20 µg

PPP1R14D Overview

Facts about Protein phosphatase 1 regulatory subunit 14D.

PPP1R14D 3D structure. Source: alphafold

Protein phosphatase 1 regulatory subunit 14D (PPP1R14D)

Inhibitor of PPP1CA.
Has inhibitory activity only when phosphorylated, developing a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contractions.

Gene Information

Human
Gene Name:	PPP1R14D
Uniprot:	Q9NXH3
Entrez:	54866

Family

Belongs to:

PP1 inhibitor family

Alternative Names

CPI17-like; FLJ20251; gastrointestinal and brain-specific PP1-inhibitory protein 1; GBPI; GBPI1; GBPI-1; gut and brain phosphatase inhibitor 1; MGC119014; MGC119016; PKC-dependent PP1 inhibitory protein; protein phosphatase 1 regulatory subunit 14D; protein phosphatase 1, regulatory (inhibitor) subunit 14D

Molecular Weight

Mass (kDA):
16.508 kDA

Genomic Context


Human

Location:	15q15.1
Sequence:	15; NC_000015.10 (40815451..40828793, complement)

Tissue Specificity

Detected in colon, intestine, kidney and brain cortex.

Subcellular Localizations

Cytoplasm.

Diseases

Cardiovascular Diseases
Malignant Neoplasms
Diabetes Mellitus, Experimental
Neoplasms
Nervous System Disorder
Diabetes Mellitus

Pathways

Protein Phosphorylation
Transport
Vesicle Transport

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PPP1R14D

References

PMID: 12974676 by Liu Q.-R., et al. GBPI, a novel gastrointestinal- and brain-specific PP1-inhibitory protein, is activated by PKC and inactivated by PKA.