Tuberoinfundibular peptide of 39 residues (PTH2)

Plays a role as a potent and selective agonist of PTH2R leading to adenyl cyclase activation and intracellular calcium levels elevation. Induces protein kinase C beta activation, recruitment of beta-arrestin and PTH2R internalization.

May inhibit cell proliferation via its actions on PTH2R activation. Neuropeptide which may also have a role in spermatogenesis.