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- Table of Contents
PRKCA-binding protein Antibodies
AND PICK1 ELISA kits, PRKCA-binding protein Proteins
Many biological assays use antibodies to detect PRKCA-binding protein, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PRKCA-binding protein in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PRKCA-binding protein antibodies...
Designing an IHC experiment for PRKCA-binding protein? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the PICK1 IHC GuidePICK1 Infographic by Boster Bio
All PICK1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IP, WB
$370
Cat # M02457-1
100 μl/vial
Cat # M02457-1
100 μl/vial
PICK1 Overview
Facts about PRKCA-binding protein.
PRKCA-binding protein (PICK1)
Probable adapter protein that bind to and organize the subcellular localization of an assortment of membrane proteins comprising some PDZ recognition sequence. Involved from the clustering of different receptors, possibly by acting at the receptor internalization level.
May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel.
Gene Information
| Human | |
|---|---|
| Gene Name: | PICK1 |
| Uniprot: | Q9NRD5 |
| Entrez: | 9463 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
alpha binding protein; dJ1039K5; MGC15204; PICK; PRKCA-binding protein; PRKCABPprotein interacting with PRKCA; Protein interacting with C kinase 1; protein interacting with PRKCA 1; Protein kinase C-alpha-binding protein
Molecular Weight
Mass (kDA):
46.6 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 22q13.1 |
| Sequence: | 22; NC_000022.11 (38056311..38075704) |
Tissue Specificity
Ubiquitous.
Subcellular Localizations
Cytoplasm, perinuclear region. Membrane; Peripheral membrane protein. Membrane; Lipid-anchor. Cell junction, synapse, postsynaptic density. Cell junction, synapse, synaptosome. Cytoplasm, cytoskeleton. Also membrane-associated, present at excitatory synapses.
Diseases
- Depressive Disorder
- Nervousness
- Schizophrenia
- Pain
- Malignant Neoplasms
- Infertility
- Male Infertility
- Tissue Adhesions
- Psychotic Disorders
- Neuralgia
- Epilepsy
- Cerebrovascular Accident
- Neoplasms
Interacting Proteins
- ASIC1
- ASIC2
- COIL
- HMG20A
- HSF2
- KCTD9
- MRI1
- TDO2
- THAP6
Pathways
- Localization
- Synaptic Transmission
- Endocytosis
- Lipid Binding
- Transport
- Exocytosis
- Cell Death
- Pathogenesis
- Cell Adhesion
- Receptor Internalization
- Rna Interference
- Reflex
- Spermatogenesis
PTMs
- Phosphorylation
- Dephosphorylation
- Cleavage
- Ubiquitination
- Nitrosylation
Research Areas
- Signal Transduction
- Transcription Factors and Regulators
- Vision
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PICK1
bosterbio.com/bosterbio-gene-info-cards/PICK1
References
PMID: 10623590 by Takeya R., et al. Interaction of the PDZ domain of human PICK1 with class I ADP- ribosylation factors.
PMID: 12529303 by Collins J.E., et al. Reevaluating human gene annotation: a second-generation analysis of chromosome 22.