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- Table of Contents
RAB14 Antibodies
AND RAB14 ELISA kits, RAB14 Proteins
Many biological assays use antibodies to detect RAB14, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RAB14 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RAB14 antibodies...
Designing a Western blot for RAB14? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the RAB14 Western Blot GuideDesigning an IHC experiment for RAB14? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the RAB14 IHC GuideRAB14 Infographic by Boster Bio
All RAB14 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A04231-1
100 µg/vial
Cat # A04231-1
100 µg/vial
RAB14 Overview
Facts about Ras-related protein Rab-14.
Ras-related protein Rab-14 (RAB14)
Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development.
May act by regulating the kinesin KIF16B-cargo institution to endosomes (By similarity). Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N- cadherin/CDH2 shedding and cell-cell adhesion.
Gene Information
| Human | |
|---|---|
| Gene Name: | RAB14 |
| Uniprot: | P61106 |
| Entrez: | 51552 |
Family
| Belongs to: |
|---|
| small GTPase superfamily |
Alternative Names
bA165P4.3 (member RAS oncogene family); F protein-binding protein 1; FBP; RAB-14; RAB14, member RAS oncogene family; ras-related protein Rab-14; small GTP binding protein RAB14
Molecular Weight
Mass (kDA):
23.897 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9q33.2 |
| Sequence: | 9; NC_000009.12 (121178133..121201869, complement) |
Subcellular Localizations
Recycling endosome. Early endosome membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus, trans-Golgi network membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle, phagosome. Recruited to recycling endosomes by DENND6A (PubMed:22595670). Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211).
Diseases
- Malignant Neoplasms
- Neoplasms
- Malignant Neoplasm Of Lung
- Infective Disorder
- Lung Neoplasms
- Leukemia
- Neoplasm Metastasis
- Neoplasms, Experimental
- Pelvic Inflammatory Disease
- Feline Infectious Peritonitis And Pleuritis
- Malignant Tumor Of Cervix
- Carcinoma
Interacting Proteins
- EXOC5
- OCRL
Pathways
- Transport
- Localization
- Endocytic Recycling
- Rna Interference
- Phagocytosis
- Exocytosis
- Cell Proliferation
- Endocytosis
- Membrane Fusion
- Autophagy
- Cell Migration
- Phagosome Maturation
- Cytokinesis
PTMs
- Phosphorylation
Research Areas
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RAB14
bosterbio.com/bosterbio-gene-info-cards/RAB14
References
PMID: 16962593 by Proikas-Cezanne T., et al. Rab14 is part of the early endosomal clathrin-coated TGN microdomain.
PMID: 21255211 by Seto S., et al. Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes.