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- Table of Contents
RAD51B Antibodies
AND RAD51B ELISA kits, RAD51B Proteins
Many biological assays use antibodies to detect RAD51B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RAD51B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RAD51B antibodies...
Designing a Western blot for RAD51B? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the RAD51B Western Blot GuideDesigning an IHC experiment for RAD51B? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the RAD51B IHC GuideRAD51B Infographic by Boster Bio
All RAD51B Products
Product
Figures
Specificity
Applications
Price
Human
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A02658-2
100 μg/vial
Cat # A02658-2
100 μg/vial
RAD51B Overview
Facts about DNA repair protein RAD51 homolog 2.
DNA repair protein RAD51 homolog 2 (RAD51B)
Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. May promote the assembly of presynaptic RAD51 nucleoprotein filaments.
Binds single-stranded DNA and double-stranded DNA and contains DNA-dependent ATPase activity. Part of this RAD21 paralog protein complex BCDX2 which functions from the BRCA1-BRCA2-dependent HR pathway.
Gene Information
| Human | |
|---|---|
| Gene Name: | RAD51B |
| Uniprot: | O15315 |
| Entrez: | 5890 |
Family
| Belongs to: |
|---|
| RecA family |
Alternative Names
DNA repair protein RAD51 homolog 2; MGC34245; R51H2REC2hREC2; RAD51 (S. cerevisiae)-like 1; RAD51 homolog B; RAD51B; RAD51-like 1 (S. cerevisiae); RAD51-like protein 1; RecA-like protein; recombination repair protein
Molecular Weight
Mass (kDA):
42.196 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 14q24.1 |
| Sequence: | 14; NC_000014.9 (67819779..68683118) |
Tissue Specificity
Expressed in a wide range of tissues.
Subcellular Localizations
Nucleus.
Diseases
- Malignant Neoplasms
- Malignant Neoplasm Of Breast
- Neoplasms
- Mammary Neoplasms
- Genomic Instability
- Cytogenetic Abnormality
- Cell Transformation, Neoplastic
- Brain Neoplasms
- Glioma
- Uterine Fibroids
- Malignant Neoplasm Of Ovary
- Glioblastoma
- Instabilities, Chromosomal
Interacting Proteins
- FAM9B
- RAD51C
- RAD51D
- SWSAP1
Pathways
- Dna Repair
- Recombinational Repair
- Cell Cycle
- Double-strand Break Repair
- Dna Recombination
- Hypersensitivity
- Meiosis
- Localization
- Cell Proliferation
- Cell Cycle Arrest
- Gene Conversion
- Telomere Maintenance
- Cell Killing
PTMs
- Phosphorylation
Research Areas
- Breast Cancer
- Cancer
- Chromatin Research
- DNA Double Strand Break Repair
- DNA Repair
- Homologous Recombination
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RAD51B
bosterbio.com/bosterbio-gene-info-cards/RAD51B
References
PMID: 9207106 by Rice M.C., et al. Isolation of human and mouse genes based on homology to REC2, a recombinational repair gene from the fungus Ustilago maydis.
PMID: 9441753 by Albala J.S., et al. Identification of a novel human RAD51 homolog, RAD51B.