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- Table of Contents
Facts about Regucalcin.
Calcium-binding protein. Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities (By similarity).
Human | |
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Gene Name: | RGN |
Uniprot: | Q15493 |
Entrez: | 9104 |
Belongs to: |
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SMP-30/CGR1 family |
EC 3.1.1.17; gluconolactonase; GNL; RCsenescence marker protein-30; regucalcin (senescence marker protein-30); Senescence marker protein 30; SMP-30; SMP30regucalcin
Mass (kDA):
33.253 kDA
Human | |
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Location: | Xp11.3 |
Sequence: | X; NC_000023.11 (47078355..47093314) |
Cytoplasm.
A brief overview of Steven Boster's Biography and Historiography can be found here. Read on to learn more about this important scientist and his work. You may also want to read up on high-affinity primary antibodies. This type of antibody binds specifically to a target protein and is highly useful for biochemical and immunological applications. High-affinity primary antibodies can also be used for imaging, immunohistochemistry, and Western Blotting.
In 1993, Boster developed his first product and received the nickname "he who converts science in the lavatory." His innovative products ranged from IHC assays to hundreds of primary antibodies. In the late nineties, his company had become the largest catalog antibody manufacturer in China. After his success with his initial product, Boster developed his own proprietary ELISA platform, PicoKine(tm), which uses his trade secrets to deliver high-sensitivity ELISA kits.
The Historiography of Boster has been the subject of much recent media coverage, including the resurgence of the word at the start of the twenty-first century. While the term was initially a benign concept, it became a frequent part of headlines and Twitter trends after it was paired with words such as vaccine, shot, and immunity. Experts cried out for additional protection from diseases like SARS-CoV-2.
Boster Bio manufactures primary antibodies and ELISA kits with more than 16,000 scientific citations. Their antibodies are validated for use in ELISA, WB, and ICC/IF. In addition, they offer rabbit polyclonal antibodies. Whether your research focuses on cancer, developmental biology, neurosciences, or inflammation, Boster products will help you achieve your research goals. In addition, Boster guarantees the quality of their products, offering a satisfaction guarantee.
Among these products, the most important difference is the use of heavy and light chain gene usage. In addition, the antibodies are different in the number of mutations in the light and heavy chains. These differences result in a high affinity for specific antigens. These antibodies are useful for the analysis of complex biological processes such as tumor immunohistochemistry, autoimmune diseases, and cancer research. Furthermore, Boster Bio high-affinity antibodies have an excellent affinity to target human cancer cells.
A high-affinity antibody is able to neutralize ricin in vitro, but its potency varies between different antibodies. MH77 is able to neutralize ricin by binding to its epitope. However, the antibody MH49 does not fit within this trend, indicating that it is not useful for cancer immunotherapy. It is a good choice for determining the affinity of antibodies to ricin in your research.
While ELISA may not be the most efficient way to identify cancer antigens, it can help scientists analyze a wide range of samples. It is a powerful method of measuring specific analytes from a crude preparation. In fact, Boster Bio offers a wide range of high-affinity primary antibodies for research and development. Its high-affinity primary antibodies allow for more questions to be asked and provide contextual data.
As a result, this library contains clones with distinct germline gene sequences. These clones were compared to the Rhesus germline gene sequences, with the most closely related genes assigned to each clone. Multiple alignments enabled the generation of a phylogenetic tree. The sequences of two antibodies from the same library are similar. This may reflect a process called somatic hypermutation.
The tetramer consists of alpha, beta, and gamma chains. These chains are also subunits of the other Fc receptors. When exposed to a foreign substance, the immune system releases a molecule that can cause an allergic reaction. High-affinity antibodies, which can be used in research, are known as monoclonal antibodies. However, there are some companies that have been in the business of developing and selling ELISA kits for more than 20 years.
PMID: 7548213 by Fujita T., et al. Isolation of cDNA clone encoding human homologue of senescence marker protein-30 (SMP30) and its location on the X chromosome.
PMID: 10677570 by Misawa H., et al. Transcript heterogeneity of the human gene for Ca2+-binding protein regucalcin.