This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Designing a Western blot for RGS1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the RGS1 Western Blot GuideFacts about Regulator of G-protein signaling 1.
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form (PubMed:10480894, PubMed:18434541). .
| Human | |
|---|---|
| Gene Name: | RGS1 |
| Uniprot: | Q08116 |
| Entrez: | 5996 |

| Belongs to: |
|---|
| No superfamily |

1R20Early response protein 1R20; BL34B-cell activation protein BL34; IER1; IR20immediate-early response 1, B-cell specific; regulator of G-protein signaling 1; regulator of G-protein signalling 1
Mass (kDA):
23.858 kDA

| Human | |
|---|---|
| Location: | 1q31.2 |
| Sequence: | 1; NC_000001.11 (192575773..192580024) |
Detected in peripheral blood monocytes (PubMed:10480894). Expression is relatively low in B-cells and chronic lymphocytic leukemia B-cells; however, in other types of malignant B-cell such as non-Hodgkin lymphoma and hairy cell leukemia, expression is constitutively high (PubMed:8473738).
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol.





PMID: 8473738 by Hong J.X., et al. Isolation and characterization of a novel B cell activation gene.
PMID: 8241276 by Newton J.S., et al. A B cell specific immediate early human gene is located on chromosome band 1q31 and encodes an alpha helical basic phosphoprotein.