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- Table of Contents
RHOB Antibodies
AND RHOB ELISA kits, RHOB Proteins
Many biological assays use antibodies to detect RHOB, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RHOB in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RHOB antibodies...
Designing a Western blot for RHOB? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the RHOB Western Blot GuideRHOB Infographic by Boster Bio
All RHOB Products
Product
Figures
Specificity
Applications
Price
Anti-Bim/BCL2L11 Antibody Picoband®
1 Citations
Human, Mouse
Flow Cytometry, IHC, WB
$370
Cat # A01552-4
100 μg/vial
Cat # A01552-4
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01551-1
100 μg/vial
Cat # A01551-1
100 μg/vial
Human, Monkey, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # A01550-1
100 μg/vial
Cat # A01550-1
100 μg/vial
RHOB Overview
Facts about Rho-related GTP-binding protein RhoB.
Rho-related GTP-binding protein RhoB (RHOB)
Mediates apoptosis in neoplastically transformed cells after DNA damage. Not vital for growth but affects cell adhesion and growth factor signaling in transformed cells.
Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a range of proteins.
Gene Information
| Human | |
|---|---|
| Gene Name: | RHOB |
| Uniprot: | P62745 |
| Entrez: | 388 |
Family
| Belongs to: |
|---|
| small GTPase superfamily |
Alternative Names
ARH6MSTP081; ARHBAplysia RAS-related homolog 6; h6; MST081; oncogene RHO H6; ras homolog gene family, member B; Rho cDNA clone 6; RHOH6RhoB; rho-related GTP-binding protein RhoB
Molecular Weight
Mass (kDA):
22.123 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2p24.1 |
| Sequence: | 2; NC_000002.12 (20447074..20449440) |
Subcellular Localizations
Late endosome membrane; Lipid-anchor. Cell membrane; Lipid-anchor. Nucleus. Cleavage furrow. Late endosomal membrane (geranylgeranylated form). Plasma membrane (farnesylated form). Also detected at the nuclear margin and in the nucleus. Translocates to the equatorial region before furrow formation in a ECT2-dependent manner.
Diseases
- Malignant Neoplasms
- Neoplasms
- Tissue Adhesions
- Genotoxic Stress
- Cell Transformation, Neoplastic
- Crest Syndrome
- Degenerative Polyarthritis
- Malignant Neoplasm Of Breast
- Carcinoma
- Neoplasm Metastasis
- Malignant Paraganglionic Neoplasm
- Cell Invasion
- Lung Neoplasms
Interacting Proteins
- TNFAIP1
Pathways
- Cell Cycle
- Cell Growth
- Cell Proliferation
- Localization
- Cell Adhesion
- Translation
- Cell Death
- Delamination
- Cell Migration
- Sensitization
- Dna Replication
- S Phase
- Pathogenesis
PTMs
- Ribosylation
- Phosphorylation
- Geranylgeranylation
Research Areas
- Angiogenesis
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RHOB
bosterbio.com/bosterbio-gene-info-cards/RHOB
References
PMID: 3283705 by Chardin P., et al. Coding sequence of human rho cDNAs clone 6 and clone 9.
PMID: 3888408 by Madaule P., et al. A novel ras-related gene family.
1 Publications of Boster RHOB Antibodies & ELISA Kits
- PubMed ID: 10.1097/FJC.0000000000000371, CYP2J2 Overexpression Increases EETs and Protects Against HFD-Induced Atheroscle...
*More publications can be found for each product on its corresponding product page