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- Table of Contents
3 Q&As
Facts about Rho-related GTP-binding protein RhoB.
Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a range of proteins.
| Human | |
|---|---|
| Gene Name: | RHOB |
| Uniprot: | P62745 |
| Entrez: | 388 |

| Belongs to: |
|---|
| small GTPase superfamily |

ARH6MSTP081; ARHBAplysia RAS-related homolog 6; h6; MST081; oncogene RHO H6; ras homolog gene family, member B; Rho cDNA clone 6; RHOH6RhoB; rho-related GTP-binding protein RhoB
Mass (kDA):
22.123 kDA

| Human | |
|---|---|
| Location: | 2p24.1 |
| Sequence: | 2; NC_000002.12 (20447074..20449440) |
Late endosome membrane; Lipid-anchor. Cell membrane; Lipid-anchor. Nucleus. Cleavage furrow. Late endosomal membrane (geranylgeranylated form). Plasma membrane (farnesylated form). Also detected at the nuclear margin and in the nucleus. Translocates to the equatorial region before furrow formation in a ECT2-dependent manner.






PMID: 3283705 by Chardin P., et al. Coding sequence of human rho cDNAs clone 6 and clone 9.
PMID: 3888408 by Madaule P., et al. A novel ras-related gene family.