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- Table of Contents
Designing a Western blot for Acyl-CoA desaturase? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SCD Western Blot GuideDesigning an IHC experiment for Acyl-CoA desaturase? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SCD IHC Guide6 Citations
1 Citations
Facts about Acyl-CoA desaturase.
Gives rise to a mix of 16:1 and 18:1 unsaturated fatty acids (PubMed:15610069). Plays an essential role in lipid biosynthesis.
| Human | |
|---|---|
| Gene Name: | SCD |
| Uniprot: | O00767 |
| Entrez: | 6319 |

| Belongs to: |
|---|
| fatty acid desaturase type 1 family |

FADS5; MSTP008; SCD1; SCD-1; SCDOS; Stearoyl-CoA desaturase
Mass (kDA):
41.523 kDA

| Human | |
|---|---|
| Location: | 10q24.31 |
| Sequence: | 10; NC_000010.11 (100347233..100364826) |
Detected in fetal liver, lung and brain. Highly expressed in adult adipose tissue, and at lower levels in adult brain and lung.
Endoplasmic reticulum membrane; Multi-pass membrane protein.




PMID: 10229681 by Zhang L., et al. Human stearoyl-CoA desaturase: alternative transcripts generated from a single gene by usage of tandem polyadenylation sites.
PMID: 11415448 by Zhang L., et al. Isolation and characterization of the human stearoyl-CoA desaturase gene promoter: requirement of a conserved CCAAT cis-element.
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