This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
SDHA Antibodies
AND SDHA ELISA kits, SDHA Proteins
Many biological assays use antibodies to detect SDHA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SDHA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SDHA antibodies...
Designing a Western blot for SDHA? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SDHA Western Blot GuideDesigning an IHC experiment for SDHA? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SDHA IHC GuideSDHA Infographic by Boster Bio
All SDHA Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # PB9433
100 μg/vial
Cat # PB9433
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # PA1717
100 μg/vial
Cat # PA1717
100 μg/vial
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01754-2
100 μg/vial
Cat # A01754-2
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # A01753
100 μg/vial
Cat # A01753
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01753
100 μl
Cat # M01753
100 μl
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M01753-2
20μL, 40μL, 100μL, 200μL
Cat # M01753-2
20μL, 40μL, 100μL, 200μL
SDHA Overview
Facts about Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial.
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (SDHA)
Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) which is included in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (PubMed:24781757). Can function as a tumor suppressor (PubMed:20484225).
.
Gene Information
| Human | |
|---|---|
| Gene Name: | SDHA |
| Uniprot: | P31040 |
| Entrez: | 6389 |
Family
| Belongs to: |
|---|
| FAD-dependent oxidoreductase 2 family |
Alternative Names
CMD1GG; EC 1.3.5.1; Fp; SDH1; SDH2; SDHFmitochondrial; succinate dehydrogenase complex flavoprotein subunit; succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
Molecular Weight
Mass (kDA):
72.692 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5p15.33 |
| Sequence: | 5; NC_000005.10 (218223..264816) |
Subcellular Localizations
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Diseases
- Neoplasms
- Paraganglioma
- Pheochromocytoma
- Malignant Neoplasms
- Von Hippel-lindau Syndrome
- Neurofibromatosis 1
- Adrenal Gland Neoplasms
- Cell Transformation, Neoplastic
- Carcinoma
- Gastrointestinal Stromal Tumors
- Malignant Paraganglionic Neoplasm
- Hereditary Paraganglioma
Interacting Proteins
- PTPN3
- SDHAF2
- SDHB
Pathways
- Pathogenesis
- Transport
- Reverse Transcription
- Electron Transport
- Tricarboxylic Acid Cycle
- Oxidative Phosphorylation
- Cell Death
- Electron Transport Chain
- Localization
- Virulence
- Fermentation
- Angiogenesis
- Rna Interference
PTMs
- Phosphorylation
- Oxidation
- Cleavage
- Methylation
Research Areas
- Hypoxia
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SDHA
bosterbio.com/bosterbio-gene-info-cards/SDHA
References
PMID: 7798181 by Hirawake H., et al. Human complex II (succinate-ubiquinone oxidoreductase): cDNA cloning of the flavoprotein (Fp) subunit of liver mitochondria.
PMID: 8142412 by Morris A.A.M., et al. The cDNA sequence of the flavoprotein subunit of human heart succinate dehydrogenase.