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- Table of Contents
SDHB Antibodies
AND SDHB ELISA kits, SDHB Proteins
Many biological assays use antibodies to detect SDHB, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SDHB in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SDHB antibodies...
Designing a Western blot for SDHB? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SDHB Western Blot GuideDesigning an IHC experiment for SDHB? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SDHB IHC GuideSDHB Infographic by Boster Bio
All SDHB Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # M01090-1
100 μg/vial
Cat # M01090-1
100 μg/vial
Human, Mouse, Rat
IHC, WB
$370
Cat # M01090-2
100 μg/vial
Cat # M01090-2
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IHC, WB
$370
Cat # M01090
100 μl
Cat # M01090
100 μl
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M01090-5
20μL, 40μL, 100μL, 200μL
Cat # M01090-5
20μL, 40μL, 100μL, 200μL
SDHB Overview
Facts about Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial.
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (SDHB)
Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transfer chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). .
Gene Information
| Human | |
|---|---|
| Gene Name: | SDHB |
| Uniprot: | P21912 |
| Entrez: | 6390 |
Family
| Belongs to: |
|---|
| succinate dehydrogenase/fumarate reductase iron-sulfur protein family |
Alternative Names
EC 1.3.5.1; FLJ92337; IP; Iron-sulfur subunit of complex II; PGL4; SDH; SDH1; SDH2; SDHIP; succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
Molecular Weight
Mass (kDA):
31.63 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p36.13 |
| Sequence: | 1; NC_000001.11 (17018722..17054032, complement) |
Subcellular Localizations
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Diseases
- Paraganglioma
- Neoplasms
- Pheochromocytoma
- Adrenal Gland Neoplasms
- Von Hippel-lindau Syndrome
- Malignant Neoplasms
- Malignant Paraganglionic Neoplasm
- Neurofibromatosis 1
- Head And Neck Neoplasms
- Hereditary Paraganglioma
- Neoplasm Metastasis
- Neurofibromatoses
- Germline Mutation Abnormality
Interacting Proteins
- HSCB
- ISCU
- SDHA
- SDHAF1
Pathways
- Pathogenesis
- Transport
- Electron Transport
- Localization
- Electron Transport Chain
- Angiogenesis
- Tricarboxylic Acid Cycle
- Oxidative Phosphorylation
- Methylation
- Glycolysis
- Secretion
- Cell Proliferation
- Excretion
PTMs
- Methylation
- Phosphorylation
- Reduction
- Cleavage
Research Areas
- Cancer
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SDHB
bosterbio.com/bosterbio-gene-info-cards/SDHB
References
PMID: 7622059 by Au H.C., et al. Structural organization of the gene encoding the human iron-sulfur subunit of succinate dehydrogenase.
PMID: 16751257 by Kullberg M., et al. Housekeeping genes for phylogenetic analysis of eutherian relationships.