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- Table of Contents
SEC23A Antibodies
AND SEC23A ELISA kits, SEC23A Proteins
Many biological assays use antibodies to detect SEC23A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SEC23A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SEC23A antibodies...
Designing a Western blot for SEC23A? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SEC23A Western Blot GuideDesigning an IHC experiment for SEC23A? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SEC23A IHC GuideSEC23A Infographic by Boster Bio
All SEC23A Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A05287-2
100 μg/vial
Cat # A05287-2
100 μg/vial
SEC23A Overview
Facts about Protein transport protein Sec23A.
Protein transport protein Sec23A (SEC23A)
Part of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main purposes, the physical deformation of the endoplasmic reticulum membrane into vesicles along with the choice of cargo molecules for their transport to the Golgi complex.
Required for the translocation of insulin-induced glucose transporter SLC2A4/GLUT4 into the cell membrane (By similarity). .
Gene Information
| Human | |
|---|---|
| Gene Name: | SEC23A |
| Uniprot: | Q15436 |
| Entrez: | 10484 |
Family
| Belongs to: |
|---|
| SEC23/SEC24 family |
Alternative Names
CLSD; MGC26267; protein transport protein Sec23A; Sec23 (S. cerevisiae) homolog A; Sec23 homolog A (S. cerevisiae); SEC23-related protein A
Molecular Weight
Mass (kDA):
86.161 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 14q21.1 |
| Sequence: | 14; NC_000014.9 (39031919..39103235, complement) |
Tissue Specificity
Ubiquitously expressed.
Subcellular Localizations
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol. Enriched at endoplasmic reticulum exit sites, also known as transitional endoplasmic reticulum (tER).
Diseases
- Dysplasia
- Stomatitis
- Vesicular Stomatitis
- Craniofacial Abnormalities
- Endoplasmic Reticulum Stress
- Neoplasm Metastasis
- Congenital Dyserythropoietic Anemia
- Congenital Dyserythropoietic Anemia, Type Ii
- Fibrosis
- Neoplasms
- Hereditary Diseases
Interacting Proteins
- CDK16
- SEC24C
Pathways
- Transport
- Secretion
- Secretory Pathway
- Protein Transport
- Localization
- Golgi Localization
- Protein Secretion
- Protein Folding
- Intracellular Transport
- Cell Proliferation
- Cellular Homeostasis
- Fertilization
- Proteolysis
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SEC23A
bosterbio.com/bosterbio-gene-info-cards/SEC23A
References
PMID: 8898360 by Paccaud J.-P., et al. Cloning and functional characterization of mammalian homologues of the COPII component Sec23.
PMID: 17192411 by Bhattacharyya D., et al. Two mammalian Sec16 homologues have nonredundant functions in endoplasmic reticulum (ER) export and transitional ER organization.