SEC23A Antibodies

AND SEC23A ELISA kits, SEC23A Proteins

Many biological assays use antibodies to detect SEC23A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SEC23A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SEC23A antibodies...

We validate the specificity of these antibodies to SEC23A by testing them on tissues known to express SEC23A positively and negatively. Browse below to find the SEC23A antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SEC23A Infographic by Boster Bio

All SEC23A Products

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Specificity

Applications

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Anti-SEC23 Monoclonal Antibody

1 Q&As

Western blot analysis of SEC23 expression in HeLa cell lysate

Human

Flow Cytometry, WB

$370
Cat # M05287
100 μl

Anti-SEC23A Antibody

Western blot analysis of extracts of various cell lines, using Sec23A antibody at 1:3000 dilution

Human, Mouse, Rat

$405
Cat # A05287
100ul

Anti-SEC23 Antibody

ICC staining SEC23 in HepG2 cells (green)

Human, Mouse

Flow Cytometry, IHC, ICC, WB

$405
Cat # A05287-1
100ul

Anti-SEC23A Antibody Picoband®

1 Citations 1 Q&As

Western blot analysis of SEC23A using anti-SEC23A antibody (A05287-2)

IHC analysis of SEC23A using anti-SEC23A antibody (A05287-2)

IF analysis of SEC23A using anti-SEC23A antibody (A05287-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A05287-2
100 μg/vial

SEC23 (SEC23A) (NM_006364) Human Over-expression Lysate

Human

$628
Cat # LS010484
20 µg, 100 µg

SEC23A Overview

Facts about Protein transport protein Sec23A.

SEC23A 3D structure. Source: alphafold

Protein transport protein Sec23A (SEC23A)

Part of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main purposes, the physical deformation of the endoplasmic reticulum membrane into vesicles along with the choice of cargo molecules for their transport to the Golgi complex.

Required for the translocation of insulin-induced glucose transporter SLC2A4/GLUT4 into the cell membrane (By similarity). .

Gene Information

Human
Gene Name:	SEC23A
Uniprot:	Q15436
Entrez:	10484

Family

Belongs to:

SEC23/SEC24 family

Alternative Names

CLSD; MGC26267; protein transport protein Sec23A; Sec23 (S. cerevisiae) homolog A; Sec23 homolog A (S. cerevisiae); SEC23-related protein A

Molecular Weight

Mass (kDA):
86.161 kDA

Genomic Context


Human

Location:	14q21.1
Sequence:	14; NC_000014.9 (39031919..39103235, complement)

Tissue Specificity

Ubiquitously expressed.

Subcellular Localizations

Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytosol. Enriched at endoplasmic reticulum exit sites, also known as transitional endoplasmic reticulum (tER).

Diseases

Dysplasia
Stomatitis
Vesicular Stomatitis
Craniofacial Abnormalities
Endoplasmic Reticulum Stress
Neoplasm Metastasis
Congenital Dyserythropoietic Anemia
Congenital Dyserythropoietic Anemia, Type Ii
Fibrosis
Neoplasms
Hereditary Diseases

Anemia
Pathological Dilatation
Cystic Fibrosis
Williams Syndrome
Malignant Neoplasm Of Breast
Orbital Separation Excessive

Interacting Proteins

CDK16
SEC24C

Pathways

Transport
Secretion
Secretory Pathway
Protein Transport
Localization
Golgi Localization
Protein Secretion
Protein Folding
Intracellular Transport
Cell Proliferation
Cellular Homeostasis
Fertilization
Proteolysis

Erythrocyte Development
Spermatogenesis
Cytokinesis
Lateral Growth
Chondrocyte Development
Lipid Homeostasis
Cell Differentiation

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SEC23A

References

PMID: 8898360 by Paccaud J.-P., et al. Cloning and functional characterization of mammalian homologues of the COPII component Sec23.

PMID: 17192411 by Bhattacharyya D., et al. Two mammalian Sec16 homologues have nonredundant functions in endoplasmic reticulum (ER) export and transitional ER organization.