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ADP/ATP translocase 3 Antibodies
AND SLC25A6 ELISA kits, ADP/ATP translocase 3 Proteins
Many biological assays use antibodies to detect ADP/ATP translocase 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ADP/ATP translocase 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ADP/ATP translocase 3 antibodies...
Designing an IHC experiment for ADP/ATP translocase 3? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SLC25A6 IHC GuideSLC25A6 Infographic by Boster Bio
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SLC25A6 Overview
Facts about ADP/ATP translocase 3.
ADP/ATP translocase 3 (SLC25A6)
Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that activates apoptosis.
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Gene Information
| Human | |
|---|---|
| Gene Name: | SLC25A6 |
| Uniprot: | P12236 |
| Entrez: | 293 |
Family
| Belongs to: |
|---|
| mitochondrial carrier (TC 2.A.29) family |
Alternative Names
Adenine nucleotide translocator 3; ADP; ADP/ATP translocase 3; ADP/ATP translocator of liver; ANT 2; ANT 3; ANT3AAC3; ANT3Y; ATP carrier protein 3; ATP carrier protein; ATP carrier protein, isoform T2; ATP carrier protein, liver; MGC17525; solute carrier family 25 (mitochondrial carrier; adenine nucleotidetranslocator), member 6; Solute carrier family 25 member 6
Molecular Weight
Mass (kDA):
32.866 kDA
Genomic Context
| Human | |
|---|---|
| Location: | Xp22.33 and Yp11.2 |
| Sequence: | X|Y; NC_000023.11 (1386152..1392113, complement) |
Subcellular Localizations
Mitochondrion inner membrane; Multi-pass membrane protein. The complex formed with ARL2BP, ARL2 and SLC25A6 is expressed in mitochondria.
Diseases
- Pituitary Diseases
- Fetal Death
Interacting Proteins
- AP2B1
- KRT31
- LRRK2
- LZTS2
- MTUS2
- NOTCH2NL
- TEKT4
- TRAF1
- TRIM23
- TRIP6
Pathways
- Transposition
- Translation
- Gene Silencing
- Cell Cycle
- Male Meiosis
- Gluconeogenesis
- Regulation Of Gene Expression
- Sex Determination
- Meiosis
PTMs
- Acetylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC25A6
bosterbio.com/bosterbio-gene-info-cards/SLC25A6
References
PMID: 2541251 by Cozens A.L., et al. DNA sequences of two expressed nuclear genes for human mitochondrial ADP/ATP translocase.
PMID: 2829183 by Houldsworth J., et al. Two distinct genes for ADP/ATP translocase are expressed at the mRNA level in adult human liver.