Zinc transporter ZIP1 Antibodies

AND SLC39A1 ELISA kits, Zinc transporter ZIP1 Proteins

Many biological assays use antibodies to detect Zinc transporter ZIP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Zinc transporter ZIP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Zinc transporter ZIP1 antibodies...

We validate the specificity of these antibodies to Zinc transporter ZIP1 by testing them on tissues known to express SLC39A1 positively and negatively. Browse below to find the SLC39A1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC39A1 Infographic by Boster Bio

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Anti-ZIP1 SLC39A1 Antibody

Western blot analysis of ZIP1 in mouse kidney tissue lysate with ZIP1 antibody at (A) 1 and (B) 2 μg/mL

Immunohistochemistry of ZIP1 in human kidney tissue with ZIP1 antibody at 2

Immunofluorescence of ZIP1 in human kidney tissue with ZIP1 antibody at 20 μg/mL

Human, Mouse

ELISA, IF, IHC-P, WB

$481
Cat # A03886
0.1 mg

SLC39A1 (NM_014437) Human Over-expression Lysate

Human

$628
Cat # LS027173
20 µg, 100 µg

SLC39A1 Overview

Facts about Zinc transporter ZIP1.

SLC39A1 3D structure. Source: alphafold

Zinc transporter ZIP1 (SLC39A1)

Mediates zinc uptake. May function as a significant endogenous zinc uptake transporter in several cells of the body.

Responsible for the rapid uptake and accumulation of physiologically effective zinc in prostate cells. .

Gene Information

Human
Gene Name:	SLC39A1
Uniprot:	Q9NY26
Entrez:	27173

Family

Belongs to:

ZIP transporter (TC 2.A.5) family

Alternative Names

CGI-08; CGI-71; IRT1; solute carrier family 39 (zinc transporter), member 1; solute carrier family 39 (zinc transporter), member 3; ZIP1; ZIP-1

Molecular Weight

Mass (kDA):
34.25 kDA

Genomic Context


Human

Location:	1q21.3
Sequence:	1; NC_000001.11 (153959099..153968184, complement)

Tissue Specificity

Ubiquitous. Expressed in most adult and fetal tissues including the epidermis.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Shows a vesicular localization corresponding partially to the endoplasmic reticulum in several epithelial cell lines.

Diseases

Malignant Neoplasms
Prostatic Neoplasms
Zinc Deficiency Disorder
Malignant Neoplasm Of Prostate
Malignant Paraganglionic Neoplasm
Neoplasms
Hemochromatosis
Carcinogenesis
Adenocarcinoma
Malignant Neoplasm Of Breast
Congenital Abnormality
Liver Carcinoma

Juvenile Hemochromatosis
Liver Neoplasms
Tumor Progression
Neurodegenerative Disorders
Acute Erythroblastic Leukemia
Nerve Degeneration
Iron Overload

Pathways

Transport
Cell Death
Cell Proliferation
Localization
Immune Response
Gene Silencing
Endocytosis
Pathogenesis
Secretion
Cell Adhesion
Osteoblast Differentiation
Aging
Sensitization

Cell Cycle
Meiosis I
Wound Healing
Embryonic Morphogenesis
Meiosis
Glucagon Secretion
Hormone Secretion

PTMs

Demethylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC39A1

References

PMID: 10610721 by Lioumi M., et al. Isolation and characterization of human and mouse ZIRTL, a member of the IRT1 family of transporters, mapping within the epidermal differentiation complex.

PMID: 11696349 by Milon B., et al. Differential subcellular localization of hZip1 in adherent and non- adherent cells.