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- Table of Contents
Facts about Antileukoproteinase.
major. Down-regulates responses to bacterial lipopolysaccharide (LPS) (By similarity).
| Human | |
|---|---|
| Gene Name: | SLPI |
| Uniprot: | P03973 |
| Entrez: | 6590 |

| Belongs to: |
|---|
| No superfamily |

ALK1; ALPProtease inhibitor WAP4; antileukoproteinase; BLPISeminal proteinase inhibitor; HUSI; HUSI-I; Mucus proteinase inhibitor; secretory leukocyte peptidase inhibitor; secretory leukocyte protease inhibitor (antileukoproteinase); Secretory leukocyte protease inhibitor; SLPI; WAP four-disulfide core domain protein 4; WAP4HUSI-1; WFDC4MPI
Mass (kDA):
14.326 kDA

| Human | |
|---|---|
| Location: | 20q13.12 |
| Sequence: | 20; NC_000020.11 (45252239..45254564, complement) |
Detected in blood plasma (PubMed:24352879). Detected in bone marrow myeloid cells (PubMed:24352879). Detected in airway sputum (PubMed:2039600). Detected in parotid gland secretions (PubMed:3462719). Detected in seminal plasma (at protein level) (PubMed:3485543). Detected in uterus cervix (PubMed:3533531).
Secreted.






PMID: 3533531 by Heinzel R., et al. Molecular cloning and expression of cDNA for human antileukoprotease from cervix uterus.
PMID: 3640338 by Stetler G., et al. Isolation and sequence of a human gene encoding a potent inhibitor of leukocyte proteases.