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- Table of Contents
Spermine oxidase Antibodies
AND SMOX ELISA kits, Spermine oxidase Proteins
Many biological assays use antibodies to detect Spermine oxidase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Spermine oxidase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Spermine oxidase antibodies...
Designing an IHC experiment for Spermine oxidase? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SMOX IHC GuideSMOX Infographic by Boster Bio
All SMOX Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A05519-2
100 μg/vial
Cat # A05519-2
100 μg/vial
Human, Monkey, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A05530-1
100 μg/vial
Cat # A05530-1
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A05545-2
100 μg/vial
Cat # A05545-2
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A05520-2
100 µg/vial
Cat # A05520-2
100 µg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A05519-1
100 μg/vial
Cat # A05519-1
100 μg/vial
SMOX Overview
Facts about Spermine oxidase.
Spermine oxidase (SMOX)
Flavoenzyme that catalyzes the oxidation of spermine to spermidine. Can also use N(1)-acetylspermine and spermidine as substrates, with different affinity depending on the isoform (isozyme) and on the experimental conditions.
Plays an essential role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. May contribute to beta-alanine production through aldehyde dehydrogenase conversion of 3-amino-propanal.
Gene Information
| Human | |
|---|---|
| Gene Name: | SMOX |
| Uniprot: | Q9NWM0 |
| Entrez: | 54498 |
Family
| Belongs to: |
|---|
| flavin monoamine oxidase family |
Alternative Names
C20orf16; chromosome 20 open reading frame 16; EC 1.5.3.16; flavin containing amine oxidase; flavin-containing spermine oxidase; FLJ20746; MGC1010; PAO; PAO-1; PAOH1; Polyamine oxidase 1; putative cyclin G1 interacting protein; SMOdJ779E11.1; spermine oxidase
Molecular Weight
Mass (kDA):
61.819 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 20p13 |
| Sequence: | 20; NC_000020.11 (4148779..4187747) |
Tissue Specificity
Widely expressed. Expressed in human tumor cell lines. Isoform 4 is only found in an embryonal kidney cell line.
Subcellular Localizations
[Isoform 1]: Cytoplasm. Nucleus.; [Isoform 4]: Cytoplasm. Nucleus.; [Isoform 6]: Cytoplasm. Nucleus.
Diseases
- Pre-eclampsia
- Malignant Neoplasms
- Cancer Patients And Suicide And Depression
- Embryonal Carcinoma
- Pediatric Neoplasm
- Mood Disorders
- Oncogene Deregulation
- Neurodegenerative Disorders
- Parkinson Disease
- Patient Dependence On
- Neoplasms
- Neuroblastoma
Pathways
- Methylation
- Cell Proliferation
- Cell Death
- Axon Guidance
- Muscle Contraction
- Germ Cell Proliferation
- Pathogenesis
- Neuroblast Proliferation
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SMOX
bosterbio.com/bosterbio-gene-info-cards/SMOX
References
PMID: 11454677 by Wang Y., et al. Cloning and characterization of a human polyamine oxidase that is inducible by polyamine analogue exposure.
PMID: 12398765 by Murray-Stewart T., et al. Cloning and characterization of multiple human polyamine oxidase splice variants that code for isoenzymes with different biochemical characteristics.
1 Publications of Boster Spermine oxidase Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.tox.2017.04.001, The induction of cytochrome P450 2E1 by ethanol leads to the loss of synaptic pr...
*More publications can be found for each product on its corresponding product page