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- Table of Contents
SNAP25 Antibodies
AND SNAP25 ELISA kits, SNAP25 Proteins
Many biological assays use antibodies to detect SNAP25, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SNAP25 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SNAP25 antibodies...
Designing a Western blot for SNAP25? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SNAP25 Western Blot GuideDesigning an IHC experiment for SNAP25? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SNAP25 IHC GuideSNAP25 Infographic by Boster Bio
All SNAP25 Products
Product
Figures
Specificity
Applications
Price
Anti-SNAP25 Antibody Picoband®
2 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01625
100 μg/vial
Cat # A01625
100 μg/vial
Anti-SNAP25 Rabbit Monoclonal Antibody
2 Citations
Human, Mouse, Rat
IP, IF, ICC, WB
$370
Cat # M01625
100 μl
Cat # M01625
100 μl
Human, Mouse, Rat
ELISA
$480
Cat # EKC1533
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1533
1 kit, containing one 96-well plate and all necessary reagents
SNAP25 Overview
Facts about Synaptosomal-associated protein 25.
Synaptosomal-associated protein 25 (SNAP25)
t-SNARE involved in the molecular regulation of neurotransmitter release. May play an essential role in the synaptic function of specific neuronal systems.
Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF.
Gene Information
| Human | |
|---|---|
| Gene Name: | SNAP25 |
| Uniprot: | P60880 |
| Entrez: | 6616 |
Family
| Belongs to: |
|---|
| SNAP-25 family |
Alternative Names
bA416N4.2; dJ1068F16.2; FLJ23079; resistance to inhibitors of cholinesterase 4 homolog; RIC4; RIC-4; SEC9; SNAP25; SNAP-25SNAP; SUP; Super protein; Synaptosomal-associated 25 kDa protein; synaptosomal-associated protein 25; synaptosomal-associated protein, 25kD; synaptosomal-associated protein, 25kDa
Molecular Weight
Mass (kDA):
23.315 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 20p12.2 |
| Sequence: | 20; NC_000020.11 (10218830..10307420) |
Tissue Specificity
Neurons of the neocortex, hippocampus, piriform cortex, anterior thalamic nuclei, pontine nuclei, and granule cells of the cerebellum.
Subcellular Localizations
Cytoplasm, perinuclear region. Cell membrane; Lipid-anchor. Cell junction, synapse, synaptosome. Photoreceptor inner segment. Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region. Colocalizes with KCNB1 at the cell membrane (By similarity). Colocalizes with PLCL1 at the cell membrane (By similarity).
Diseases
- Nervousness
- Attention Deficit Hyperactivity Disorder
- Schizophrenia
- Tetanus
- Alzheimer's Disease
- Pituitary Diseases
- Malnutrition
- Botulism
- Neoplasms
- Congenital Ocular Coloboma (disorder)
- Mental Disorders
- Tissue Adhesions
- Pheochromocytoma
Interacting Proteins
- CPLX1
- STX1A
- Stx1a
- ZDHHC17
Pathways
- Exocytosis
- Secretion
- Membrane Fusion
- Localization
- Transport
- Vesicle Docking
- Vesicle Fusion
- Synaptic Transmission
- Synaptic Vesicle Exocytosis
- Proteolysis
- Insulin Secretion
- Synaptic Vesicle Fusion
- Endocytosis
PTMs
- Cleavage
- Phosphorylation
- Palmitoylation
- Acylation
- Ribosylation
- Dephosphorylation
- Acetylation
- Carboxylation
- Nitrosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SNAP25
bosterbio.com/bosterbio-gene-info-cards/SNAP25
References
PMID: 8112622 by Bark I.C., et al. Human cDNA clones encoding two different isoforms of the nerve terminal protein SNAP-25.
PMID: 8056350 by Zhao N., et al. Cloning and sequence analysis of the human SNAP25 cDNA.
4 Publications of Boster SNAP25 Antibodies & ELISA Kits
- PubMed ID: 10.1080/00207454.2017.1387115, Effects of spontaneous recurrent seizures on cognitive function via modulation o...
- PubMed ID: 10.1016/j.tox.2017.03.021, Disruption of glutamate neurotransmitter transmission is modulated by SNAP-25 in...
- PubMed ID: 32930942, Guan Y,Chen X,Zhao B,Shi Y,Han F.What Happened in the Hippocampal Axon in a Rat ...
- PubMed ID: 28761431, Zhong ZQ, Xiang Y, Hu X, Wang YC, Zeng X, Wang XM, Xia QJ, Wang TH, Zhang X. Neu...
*More publications can be found for each product on its corresponding product page