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- Table of Contents
SNW1 Antibodies
AND SNW1 ELISA kits, SNW1 Proteins
Many biological assays use antibodies to detect SNW1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SNW1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SNW1 antibodies...
Designing an IHC experiment for SNW1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SNW1 IHC GuideSNW1 Infographic by Boster Bio
All SNW1 Products
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SNW1 Overview
Facts about SNW domain-containing protein 1.
SNW domain-containing protein 1 (SNW1)
Involved in pre-mRNA splicing as part of the spliceosome (PubMed:11991638, PubMed:28502770, PubMed:28076346). Is required in the particular splicing of CDKN1A pre-mRNA; the function probably involves the recruitment of U2AF2 into the mRNA.
Is proposed to recruit PPIL1 into the spliceosome. May be involved in cyclin-D1/CCND1 mRNA stability throughout the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.
Gene Information
| Human | |
|---|---|
| Gene Name: | SNW1 |
| Uniprot: | Q13573 |
| Entrez: | 22938 |
Family
| Belongs to: |
|---|
| SNW family |
Alternative Names
Bx42; homolog of Drosophila BX42; MGC119379; NCoA-62; Nuclear protein SkiP; Nuclear receptor coactivator NCoA-62; nuclear receptor coactivator, 62-kD; Prp45; PRPF45; SKI interacting protein; Ski-interacting protein; SKIPSKIIP; SNW domain containing 1; SNW domain-containing protein 1
Molecular Weight
Mass (kDA):
61.494 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 14q24.3 |
| Sequence: | 14; NC_000014.9 (77717599..77761156, complement) |
Subcellular Localizations
Nucleus.
Diseases
- Neoplasms
- Malignant Neoplasms
- Mammary Neoplasms
- Retinoblastoma
- Muscular Dystrophy, Oculopharyngeal
- Malignant Tumor Of Colon
- Neoplasm Invasiveness
- Physiological Stress
- Dystrophy
- Muscular Dystrophy
- Neoplasm Metastasis
- Weakness
Interacting Proteins
- CEP55
- CTNNBL1
- FOXN3
- GOLGA2
- HSPB1
- IKZF1
- KRT40
- LZTS2
- MAGEA1
- MTUS2
Pathways
- Mrna Splicing
- Cell Cycle Arrest
- Rna Splicing
- Cell Division
- Cell Cycle
- Gastrulation
- Muscle Cell Differentiation
- Mitosis
- Hypersensitivity
- Mesoderm Formation
- Localization
- Spermatogenesis
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SNW1
bosterbio.com/bosterbio-gene-info-cards/SNW1
References
PMID: 9632709 by Baudino T.A., et al. Isolation and characterization of a novel coactivator protein, NCoA- 62, involved in vitamin D-mediated transcription.
PMID: 9569025 by Dahl R., et al. The Ski oncoprotein interacts with Skip, the human homolog of Drosophila Bx42.