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- Table of Contents
Sorting nexin-6 Antibodies
AND SNX6 ELISA kits, Sorting nexin-6 Proteins
Many biological assays use antibodies to detect Sorting nexin-6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Sorting nexin-6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Sorting nexin-6 antibodies...
Designing an IHC experiment for Sorting nexin-6? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SNX6 IHC GuideSNX6 Infographic by Boster Bio
All SNX6 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # A06545
100 µg/vial
Cat # A06545
100 µg/vial
Human, Mouse, Rat
ELISA
$540
Cat # EKC2483
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2483
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2482
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2482
1 kit, containing two 96-well plates and all necessary reagents
Human
ELISA
$540
Cat # EKC2266
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2266
1 kit, containing two 96-well plates and all necessary reagents
SNX6 Overview
Facts about Sorting nexin-6.
Sorting nexin-6 (SNX6)
Involved in several stages of intracellular trafficking. Acts in part as component of the retromer membrane-deforming SNX-BAR subcomplex (PubMed:19935774).
The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is included in endosome-to-plasma membrane transport for cargo protein recycling. The SNX-BAR subcomplex works to deform the donor membrane into a tubular profile called endosome-to-TGN transport carrier (ETC) (Probable).
Gene Information
| Human | |
|---|---|
| Gene Name: | SNX6 |
| Uniprot: | Q9UNH7 |
| Entrez: | 58533 |
Family
| Belongs to: |
|---|
| sorting nexin family |
Alternative Names
MGC3157; MSTP010; sorting nexin 6; sorting nexin-6; TFAF2; TRAF4-associated factor 2; tumor necrosis factor receptor-associated factor 4(TRAF4)-associated factor 2
Molecular Weight
Mass (kDA):
46.649 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 14q13.1 |
| Sequence: | 14; NC_000014.9 (34561093..34630148, complement) |
Subcellular Localizations
Early endosome. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle. Cytoplasm. Nucleus. Interaction with SNX1 or SNX2 promotes location at endosome membranes (PubMed:19935774). Only a minor proportion is seen in the nucleus.
Diseases
- Neoplasms
- Neoplasm Metastasis
- Malignant Neoplasm Of Breast
- Holoprosencephaly
- Malignant Neoplasms
- Sclerosis
- Congenital Ocular Coloboma (disorder)
- Microphthalmos
- Primary Neoplasm
- Multiple Sclerosis
Interacting Proteins
- BACE1
- DCTN1
- DISC1
- OPTN
- SNX1
- SNX2
Pathways
- Transport
- Localization
- Cellular Localization
- Rna Interference
- Secretion
- Phagosome Maturation
- Proteolysis
- Endocytic Recycling
- Nuclear Export
PTMs
- Phosphorylation
Research Areas
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SNX6
bosterbio.com/bosterbio-gene-info-cards/SNX6
References
PMID: 11485546 by Teasdale R.D., et al. A large family of endosome-localized proteins related to sorting nexin 1.
PMID: 11591366 by Ishibashi Y., et al. Pim-1 translocates sorting nexin 6/TRAF4-associated factor 2 from cytoplasm to nucleus.