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- Table of Contents
SOAT1 Antibodies
AND SOAT1 ELISA kits, SOAT1 Proteins
Many biological assays use antibodies to detect SOAT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SOAT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SOAT1 antibodies...
Designing a Western blot for SOAT1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SOAT1 Western Blot GuideDesigning an IHC experiment for SOAT1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SOAT1 IHC GuideSOAT1 Infographic by Boster Bio
All SOAT1 Products
Product
Figures
Specificity
Applications
Price
Anti-SOAT1 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A05096-1
100 µg/vial
Cat # A05096-1
100 µg/vial
SOAT1 Overview
Facts about Sterol O-acyltransferase 1.
Sterol O-acyltransferase 1 (SOAT1)
Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol. Plays a role in lipoprotein assembly and dietary cholesterol absorption.
Along with its acyltransferase activity, it may work as a ligase. .
Gene Information
| Human | |
|---|---|
| Gene Name: | SOAT1 |
| Uniprot: | P35610 |
| Entrez: | 6646 |
Family
| Belongs to: |
|---|
| membrane-bound acyltransferase family |
Alternative Names
ACACT; ACACT1; ACAT-1; ACATACAT1; acyl-Coenzyme A: cholesterol acyltransferase; Acyl-coenzyme A:cholesterol acyltransferase 1; Cholesterol acyltransferase 1; EC 2.3.1.26; RP11-215I23.2; SOAT1; STATSOAT; sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1; sterol O-acyltransferase 1
Molecular Weight
Mass (kDA):
64.735 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q25.2 |
| Sequence: | 1; NC_000001.11 (179293714..179358680) |
Subcellular Localizations
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Diseases
- Alzheimer's Disease
- Malignant Neoplasms
- Dyslipidemias
- Infarction
- Glaucoma, Open-angle
- Coronary Artery Disease
- Malignant Neoplasm Of Urinary Bladder
- Carcinoma
- Cardiovascular Diseases
- Myocardial Infarction
- Acute-phase Reaction
- Hyperlipidemia
- Primary Open Angle Glaucoma
Interacting Proteins
- TERF1
- UBIAD1
Pathways
- Transport
- Cell Adhesion
- Sterol Transport
- Acute-phase Response
- Cell Cycle
- Aging
- Reverse Cholesterol Transport
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SOAT1
bosterbio.com/bosterbio-gene-info-cards/SOAT1
References
PMID: 8407899 by Chang C.C.Y., et al. Molecular cloning and functional expression of human acyl-coenzyme A:cholesterol acyltransferase cDNA in mutant Chinese hamster ovary cells.
PMID: 10438503 by Lin S., et al. Human acyl-CoA:cholesterol acyltransferase-1 in the endoplasmic reticulum contains seven transmembrane domains.