SOAT1 Antibodies

AND SOAT1 ELISA kits, SOAT1 Proteins

Many biological assays use antibodies to detect SOAT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SOAT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SOAT1 antibodies...

We validate the specificity of these antibodies to SOAT1 by testing them on tissues known to express SOAT1 positively and negatively. Browse below to find the SOAT1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SOAT1 Infographic by Boster Bio

All SOAT1 Products

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Specificity

Applications

Price

Anti-Sterol O-acyltransferase 1 SOAT1 Antibody

Human, Mouse, Rat

IF, WB

$405
Cat # A05096
100ul

SOAT 1 (SOAT1) (NM_003101) Human Over-expression Lysate

Human

$628
Cat # LS006646
100 µg

Anti-SOAT1 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A05096-1
100 µg/vial

SOAT1 Overview

Facts about Sterol O-acyltransferase 1.

SOAT1 3D structure. Source: alphafold

Sterol O-acyltransferase 1 (SOAT1)

Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol. Plays a role in lipoprotein assembly and dietary cholesterol absorption.

Along with its acyltransferase activity, it may work as a ligase. .

Gene Information

Human
Gene Name:	SOAT1
Uniprot:	P35610
Entrez:	6646

Family

Belongs to:

membrane-bound acyltransferase family

Alternative Names

ACACT; ACACT1; ACAT-1; ACATACAT1; acyl-Coenzyme A: cholesterol acyltransferase; Acyl-coenzyme A:cholesterol acyltransferase 1; Cholesterol acyltransferase 1; EC 2.3.1.26; RP11-215I23.2; SOAT1; STATSOAT; sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1; sterol O-acyltransferase 1

Molecular Weight

Mass (kDA):
64.735 kDA

Genomic Context


Human

Location:	1q25.2
Sequence:	1; NC_000001.11 (179293714..179358680)

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Diseases

Alzheimer's Disease
Malignant Neoplasms
Dyslipidemias
Infarction
Glaucoma, Open-angle
Coronary Artery Disease
Malignant Neoplasm Of Urinary Bladder
Carcinoma
Cardiovascular Diseases
Myocardial Infarction
Acute-phase Reaction
Hyperlipidemia
Primary Open Angle Glaucoma

Liver Carcinoma
Dysfunction Adrenal
Tissue Adhesions
Hair Diseases
Atherosclerosis
Glaucoma
Physiological Stress

Interacting Proteins

TERF1
UBIAD1

Pathways

Transport
Cell Adhesion
Sterol Transport
Acute-phase Response
Cell Cycle
Aging
Reverse Cholesterol Transport

Proteolysis
Cholesterol Transport

PTMs

Phosphorylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SOAT1

References

PMID: 8407899 by Chang C.C.Y., et al. Molecular cloning and functional expression of human acyl-coenzyme A:cholesterol acyltransferase cDNA in mutant Chinese hamster ovary cells.

PMID: 10438503 by Lin S., et al. Human acyl-CoA:cholesterol acyltransferase-1 in the endoplasmic reticulum contains seven transmembrane domains.