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- Table of Contents
SPINT1 Antibodies
AND SPINT1 ELISA kits, SPINT1 Proteins
Many biological assays use antibodies to detect SPINT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SPINT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SPINT1 antibodies...
Designing an IHC experiment for SPINT1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SPINT1 IHC GuideSPINT1 Infographic by Boster Bio
All SPINT1 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # FEK0771
96 wells/kit, with removable strips.
Cat # FEK0771
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # EK0771
96 wells/kit, with removable strips.
Cat # EK0771
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK0772
96 wells/kit, with removable strips.
Cat # EK0772
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # FEK0772
96 wells/kit, with removable strips.
Cat # FEK0772
96 wells/kit, with removable strips.
SPINT1 Overview
Facts about Kunitz-type protease inhibitor 1.
Kunitz-type protease inhibitor 1 (SPINT1)
Inhibitor of HGF activator.
Also acts as an inhibitor of matriptase (ST14)..
Gene Information
| Human | |
|---|---|
| Gene Name: | SPINT1 |
| Uniprot: | O43278 |
| Entrez: | 6692 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
HAI; HAI1; HAI-1; hepatocyte growth factor activator inhibitor 1; Hepatocyte growth factor activator inhibitor type 1; kunitz-type protease inhibitor 1; MANSC2; serine peptidase inhibitor, Kunitz type 1; serine protease inhibitor, Kunitz type 1; SPINT1
Molecular Weight
Mass (kDA):
58.398 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 15q15.1 |
| Sequence: | 15; NC_000015.10 (40844043..40858207) |
Subcellular Localizations
Secreted.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Cell Invasion
- Prostatic Neoplasms
- Malignant Neoplasm Of Prostate
- Neoplasm Metastasis
- Neoplasm Invasiveness
- Malignant Neoplasm Of Breast
- Adenocarcinoma
- Tumor Progression
- Mammary Neoplasms
Pathways
- Localization
- Regeneration
- Proteolysis
- Cell Proliferation
- Zymogen Activation
- Invasive Growth
- Coagulation
- Angiogenesis
- Epithelial To Mesenchymal Transition
- Tissue Regeneration
- Cell Growth
- Keratinization
- Neural Tube Closure
PTMs
- Cleavage
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SPINT1
bosterbio.com/bosterbio-gene-info-cards/SPINT1
References
PMID: 9045658 by Shimomura T., et al. Hepatocyte growth factor activator inhibitor, a novel Kunitz-type serine protease inhibitor.
PMID: 10373425 by Lin C.Y., et al. Purification and characterization of a complex containing matriptase and a Kunitz-type serine protease inhibitor from human milk.