This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Osteopontin Antibodies
AND SPP1 ELISA kits, Osteopontin Proteins
Many biological assays use antibodies to detect Osteopontin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Osteopontin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Osteopontin antibodies...
Previous: CBLIF
Next: SPRR1A
SPP1 Infographic by Boster Bio
All SPP1 Products
Product
Figures
Specificity
Applications
Price
Anti-Osteopontin/SPP1 Antibody Picoband®
35 Citations 5 Q&As
Human, Mouse, Rat
ELISA, WB
$370
Cat # RP1080
100 μg/vial
Cat # RP1080
100 μg/vial
Human OPN / Osteopontin ELISA Kit PicoKine®
15 Citations 8 Q&As
Human
ELISA
$499
Cat # EK0482
96 wells/kit, with removable strips.
Cat # EK0482
96 wells/kit, with removable strips.
Mouse OPN / Osteopontin ELISA Kit PicoKine®
10 Citations 5 Q&As
Mouse
ELISA
$499
Cat # EK0483
96 wells/kit, with removable strips.
Cat # EK0483
96 wells/kit, with removable strips.
Anti-Osteopontin SPP1 Rabbit Monoclonal Antibody
21 Citations 16 Q&As
Human, Mouse
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00634
100 μl
Cat # M00634
100 μl
Human, Mouse, Rat
ELISA
$480
Cat # EKC1415
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1415
1 kit, containing one 96-well plate and all necessary reagents
Human
IHC, WB
$523
Cat # M00634-1
100 µl
Cat # M00634-1
100 µl
Human
$628
Cat # LS006696
20 µg, 100 µg
Cat # LS006696
20 µg, 100 µg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00634-2
100 μg
Cat # M00634-2
100 μg
Human
ELISA
$500
Cat # EZ0482
5 plates/kit
Cat # EZ0482
5 plates/kit
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M00634-3
20μL, 40μL, 100μL, 200μL
Cat # M00634-3
20μL, 40μL, 100μL, 200μL
SPP1 Overview
Facts about Osteopontin.
Osteopontin (SPP1)
Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix.
Probably important to cell-matrix interaction. .
Gene Information
| Human | |
|---|---|
| Gene Name: | SPP1 |
| Uniprot: | P10451 |
| Entrez: | 6696 |
Family
| Belongs to: |
|---|
| osteopontin family |
Alternative Names
BNSP; Bone sialoprotein 1; Eta-1; MGC110940; Nephropontin; OPN; Osteopontin; secreted phosphoprotein 1bone sialoprotein I, early T-lymphocyteactivation 1); secreted phosphoprotein-1 (osteopontin, bone sialoprotein); Spp1; SPP-1; SPP1/CALPHA1 fusion; Urinary stone protein; uropontin
Molecular Weight
Mass (kDA):
35.423 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q22.1 |
| Sequence: | 4; NC_000004.12 (87975650..87983411) |
Tissue Specificity
Bone. Found in plasma.
Subcellular Localizations
Secreted.
Diseases
- Neoplasms
- Tissue Adhesions
- Malignant Neoplasms
- Neoplasm Metastasis
- Inflammation
- Carcinoma
- Fibrosis
- Calcinosis
- Cell Invasion
- Kidney Diseases
- Cell Transformation, Neoplastic
- Malignant Paraganglionic Neoplasm
- Malignant Neoplasm Of Breast
Interacting Proteins
- CD44
- FAM20C
- MEOX2
- SGTA
Pathways
- Cell Adhesion
- Cell Proliferation
- Localization
- Pathogenesis
- Secretion
- Osteoblast Differentiation
- Bone Resorption
- Cell Migration
- Regeneration
- Angiogenesis
- Cell Growth
- Bone Remodeling
- Cell Differentiation
PTMs
- Phosphorylation
- Cleavage
- Glycosylation
- Methylation
- Dephosphorylation
- Acetylation
- Sulphation
- Nitrosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SPP1
bosterbio.com/bosterbio-gene-info-cards/SPP1
References
PMID: 2726470 by Kiefer M.C., et al. The cDNA and derived amino acid sequence for human osteopontin.
PMID: 1974876 by Young M.F., et al. cDNA cloning, mRNA distribution and heterogeneity, chromosomal location, and RFLP analysis of human osteopontin (OPN).
36 Publications of Boster Osteopontin Antibodies & ELISA Kits
- PubMed ID: 10.3892/etm.2015.2585, Renoprotective effects of berberine as adjuvant therapy for hypertensive patient...
- PubMed ID: 10.14744/AnatolJCardiol.2019.88555, The association between serum angiogenin and osteopontin levels and coronary col...
- PubMed ID: 10.1186/s13075-018-1547-6, Traditional Chinese medicine formula Bi-Qi capsule alleviates rheumatoid arthrit...
- PubMed ID: 10.1159/000334058, Predictive Value of Serum Bone Sialoprotein in Patients with Bone Metastasis of ...
- PubMed ID: 10.1111/febs.14754, Diminished membrane recruitment of Akt is instrumental in alcohol‐associated o...
- PubMed ID: 10.1111/aor.13622, Avβ3 single‐stranded DNA aptamer attenuates vascular restenosis via Ras‐PI3...
- PubMed ID: 10.1080/17435390.2018.1513093, Activated iRhom2 drives prolonged PM2.5 exposure-triggered renal injury in Nrf2-...
- PubMed ID: 10.1021/acsami.9b14800, Surface Epitaxial Crystallization-Directed Nanotopography for Accelerating Preos...
- PubMed ID: 10.1016/S1995-7645(13)60042-5, Expression of NF-κB and osteopontin of synovial fluid of patients with knee ost...
- PubMed ID: 10.1016/j.polymer.2020.122462, Combination of nanolamellae and PDA coating on promoting the long-term adhesion,...
- PubMed ID: 10.1016/j.msec.2018.11.006, Promoting osteoblast proliferation on polymer bone substitutes with bone-like st...
- PubMed ID: 10.1016/j.biomaterials.2021.121260, An improved osseointegration of metal implants by pitavastatin loaded multilayer...
- PubMed ID: 10.1016/j.apsusc.2019.03.193, Nanotopographical polymeric surface with mussel-inspired decoration to enhance o...
- PubMed ID: 10.1002/jbm.a.36273, Functionalizing titanium surface with PAMAM dendrimer and human BMP2 gene via la...
- PubMed ID: 10.1002/1878-0261.12399, Hypoxia‐driven paracrine osteopontin/integrin αvβ3 signaling promotes pancre...
- PubMed ID: 10.1002/1878-0261.12399, Hypoxia‐driven paracrine osteopontin/integrin αvβ3 signaling promotes pancre...
- PubMed ID: 33650080, Li X,Hu B,Wang L,Xia Q,Ni X. P2X7 receptor-mediated phenotype switching of pulmo...
- PubMed ID: -, Caiyun Mu,Ye He,Yan Hu,Menghuan Li,Maowen Chen,Rong Wang,Yang Xiang, Zhong Luo,K...
- PubMed ID: -, Chaowei Hu,Kun Zuo,Kuibao Li,Yuanfeng Gao,Mulei Chen,Roumu Hu,Ye Liu,Hongjie Chi...
- PubMed ID: 26315505 , Paracrine effect of inflammatory cytokine-activated bone marrow mesenchymal stem...
- PubMed ID: 26631755 , The interaction of MMP-2/B7-H3 in human osteoporosis
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page