STOM Antibodies

AND STOM ELISA kits, STOM Proteins

Many biological assays use antibodies to detect STOM, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with STOM in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop STOM antibodies...

We validate the specificity of these antibodies to STOM by testing them on tissues known to express STOM positively and negatively. Browse below to find the STOM antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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STOM Infographic by Boster Bio

All STOM Products

Product

Figures

Specificity

Applications

Price

STOM (NM_004099) Human Recombinant Protein

$1249
Cat # PROTP27105
20 µg

STOM (NM_004099) Human Over-expression Lysate

Human

$628
Cat # LS002040
100 µg

STOM Overview

Facts about Erythrocyte band 7 integral membrane protein.

STOM 3D structure. Source: alphafold

Erythrocyte band 7 integral membrane protein (STOM)

Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity.

Gene Information

Human
Gene Name:	STOM
Uniprot:	P27105
Entrez:	2040

Family

Belongs to:

band 7/mec-2 family

Alternative Names

BND7EPB7; EPB72erythrocyte band 7 integral membrane protein; erythrocyte membrane protein band 7.2 (stomatin); Protein 7.2b; Stomatin

Molecular Weight

Mass (kDA):
31.731 kDA

Genomic Context


Human

Location:	9q33.2
Sequence:	9; NC_000009.12 (121338987..121370304, complement)

Tissue Specificity

Detected in erythrocytes (at protein level). Widely expressed.

Subcellular Localizations

Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor; Cytoplasmic side. Membrane raft. Melanosome. Cytoplasmic vesicle. Localizes to juxtanuclear structure probably derived from the Golgi apparatus (PubMed:9243190). Colocalizes with cortical actin microfilaments at small plasma membrane protrusions (PubMed:9243190). Associates with alpha-granular lipid rafts (PubMed:12130500). Translocates from the alpha-granular lipid rafts to the cell membrane on thrombin activation and selectively enriched in released microvesicles (PubMed:121305

Diseases

Stomatocytic Anemia
Hereditary Stomatocytosis
Anemia
Anemia, Hemolytic
Anemia, Hemolytic, Congenital
Pseudohyperkalemia Cardiff
Malignant Neoplasms
Malaria
Shwachman Syndrome
Neoplasms
Dehydration

Nephrotic Syndrome
Focal Glomerulosclerosis
Xerocytosis
Acute Erythroblastic Leukemia
Malnutrition
Hemolysis (disorder)

Interacting Proteins

DVL3
SLC4A1
STOML1

Pathways

Transport
Localization
Glucose Transport
Cation Transport
Endocytosis
Methylation
Translation
Secretory Pathway
Dna Methylation
Ion Transport
Proteolysis
Glomerular Filtration
Protein Oligomerization

Drug Resistance
Flight
Nodulation
Response To Azide
Cell Cycle
Dna Modification
Mitochondrial Translation

PTMs

Cleavage
Demethylation
Phosphorylation

Methylation
Palmitoylation
Myristoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/STOM

References

PMID: 1883838 by Hiebl-Dirschmied C.M., et al. Cloning and nucleotide sequence of cDNA encoding human erythrocyte band 7 integral membrane protein.

PMID: 1547348 by Stewart G.W., et al. Isolation of cDNA coding for an ubiquitous membrane protein deficient in high Na+, low K+ stomatocytic erythrocytes.