Protein SHQ1 homolog Antibodies

AND SHQ1 ELISA kits, Protein SHQ1 homolog Proteins

Many biological assays use antibodies to detect Protein SHQ1 homolog, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein SHQ1 homolog in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein SHQ1 homolog antibodies...

We validate the specificity of these antibodies to Protein SHQ1 homolog by testing them on tissues known to express SHQ1 positively and negatively. Browse below to find the SHQ1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Protein SHQ1 homolog? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the SHQ1 IHC Guide

SHQ1 Infographic by Boster Bio

All SHQ1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-SHQ1 Antibody Picoband®

Western blot analysis of SHQ1 using anti-SHQ1 antibody (A10185-1)

IHC analysis of SHQ1 using anti-SHQ1 antibody (A10185-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A10185-1
100 μg/vial

Anti-Protein SHQ1 homolog SHQ1 Antibody

Western blot analysis of SHQ1 in human heart tissue lysate with SHQ1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide

Human

ELISA, IF, WB

$481
Cat # A10185
0.1 mg

SHQ1 (NM_018130) Human Over-expression Lysate

Human

$628
Cat # LS055164
20 µg, 100 µg

SHQ1 (NM_018130) Human Recombinant Protein

Coomassie blue staining of purified SHQ1 protein

$1249
Cat # PROTQ6PI26
20 µg

SHQ1 Overview

Facts about Protein SHQ1 homolog.

SHQ1 3D structure. Source: alphafold

Protein SHQ1 homolog (SHQ1)

Required for the quantitative accumulation of H/ACA ribonucleoproteins (RNPs), including telomerase, probably during the stabilization of DKC1, from the time of its synthesis before its association with NOP10, NHP2, and NAF1 at the nascent H/ACA RNA. .

Gene Information

Human
Gene Name:	SHQ1
Uniprot:	Q6PI26
Entrez:	55164

Family

Belongs to:

SHQ1 family

Alternative Names

DKFZp686H07226; FLJ10539; protein SHQ1 homolog; SHQ1 homolog (S. cerevisiae); Shq1p

Molecular Weight

Mass (kDA):
65.125 kDA

Genomic Context


Human

Location:	3p13
Sequence:	3; NC_000003.12 (72725702..72848475, complement)

Subcellular Localizations

Cytoplasm, cytosol. Nucleus, nucleoplasm. May at least partially shuttle between cytosol and nucleoplasm. In the nucleoplasm, exhibits a granular pattern, but is excluded from nucleoli and Cajal bodies. Absent from most H/ACA-box RNA transcription sites.

Diseases

Dyskeratosis Congenita
Dyskeratosis
X-linked Dyskeratosis Congenita
Prostatic Neoplasms
Neoplasms
Pancytopenia
Growth Retardation
Malignant Neoplasm Of Prostate

Neoplasm Metastasis
Malignant Neoplasms

Interacting Proteins

DKC1
GMCL2

Pathways

Ribosome Biogenesis
Box H/aca Snornp Assembly
Rna Processing
Cell Death
Telomere Maintenance
Localization
Rrna Processing

Chromatin Remodeling

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SHQ1

References

PMID: 19383767 by Grozdanov P.N., et al. SHQ1 is required prior to NAF1 for assembly of H/ACA small nucleolar and telomerase RNPs.