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- Table of Contents
Tafazzin Antibodies
AND TAZ ELISA kits, Tafazzin Proteins
Many biological assays use antibodies to detect Tafazzin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tafazzin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tafazzin antibodies...
Designing a Western blot for Tafazzin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the TAZ Western Blot GuideTAZ Infographic by Boster Bio
All TAZ Products
Product
Figures
Specificity
Applications
Price
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00937-1
100 µg/vial
Cat # A00937-1
100 µg/vial
Human, Mouse
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A00938-3
100 μg/vial
Cat # A00938-3
100 μg/vial
Human, Mouse, Rat
ELISA, IP, IF, IHC, ICC, WB
$370
Cat # A02672-2
100 μg/vial
Cat # A02672-2
100 μg/vial
TAZ Overview
Facts about Tafazzin.
Tafazzin (TAZ)
Some isoforms may participate in cardiolipin (CL) metabolism. .
Gene Information
| Human | |
|---|---|
| Gene Name: | TAZ |
| Uniprot: | Q16635 |
| Entrez: | 6901 |
Family
| Belongs to: |
|---|
| taffazin family |
Alternative Names
BTHSEFE; cardiomyopathy, dilated 3A (X-linked); CMD3A; EFE2FLJ27390; G4.5endocardial fibroelastosis 2; LVNCX; Protein G4.5; tafazzin; Taz1; XAP-2
Molecular Weight
Mass (kDA):
33.459 kDA
Genomic Context
| Human | |
|---|---|
| Location: | Xq28 |
| Sequence: | X; NC_000023.11 (154411539..154421726) |
Tissue Specificity
High levels in cardiac and skeletal muscle. Up to 10 isoforms can be present in different amounts in different tissues. Most isoforms are ubiquitous. Isoforms that lack the N- terminus are found in leukocytes and fibroblasts, but not in heart and skeletal muscle. Some forms appear restricted to cardiac and skeletal muscle or to leukocytes.
Subcellular Localizations
[Isoform 1]: Membrane; Single-pass membrane protein.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Membrane; Single-pass membrane protein.; [Isoform 4]: Membrane; Single-pass membrane protein.; [Isoform 5]: Membrane; Single-pass membrane protein.; [Isoform 6]: Cytoplasm.; [Isoform 7]: Membrane; Single-pass membrane protein.; [Isoform 8]: Cytoplasm.; [Isoform 9]: Cytoplasm.
Diseases
- 3-methylglutaconic Aciduria Type 2
- Cardiomyopathies
- Malignant Neoplasms
- Neoplasms
- Cardiomyopathy, Dilated
- Myopathy
- Infective Disorder
- Pneumonia
- Malignant Neoplasm Of Breast
- Cell Transformation, Neoplastic
- Genetic Diseases, X-linked
- Heart Failure
Pathways
- Cell Proliferation
- Localization
- Cell Differentiation
- Osteoblast Differentiation
- Pathogenesis
- Stem Cell Differentiation
- Mesenchymal Stem Cell Differentiation
- Excretion
- Cell Cycle
- Contact Inhibition
- Cell Growth
- Cell Migration
- Cell Adhesion
PTMs
- Phosphorylation
- Cleavage
- Methylation
- Dephosphorylation
Research Areas
- Transcription Factors and Regulators
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TAZ
bosterbio.com/bosterbio-gene-info-cards/TAZ
References
PMID: 8630491 by Bione S., et al. A novel X-linked gene, G4.5. is responsible for Barth syndrome.
PMID: 12930833 by Vaz F.M., et al. Only one splice variant of the human TAZ gene encodes a functional protein with a role in cardiolipin metabolism.
1 Publications of Boster Tafazzin Antibodies & ELISA Kits
- PubMed ID: 10.1371/journal.pone.0158376, Deficiency in Cardiolipin Reduces Doxorubicin-Induced Oxidative Stress and Mitoc...
*More publications can be found for each product on its corresponding product page