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TNFRSF1B Antibodies
AND TNFRSF1B ELISA kits, TNFRSF1B Proteins
Many biological assays use antibodies to detect TNFRSF1B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TNFRSF1B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TNFRSF1B antibodies...
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TNFRSF1B Infographic by Boster Bio
All TNFRSF1B Products
Product
Figures
Specificity
Applications
Price
Mouse, Rat
IHC, WB
$370
Cat # PB9515
100 μg/vial
Cat # PB9515
100 μg/vial
Human
ELISA
$499
Cat # EK0530
96 wells/kit, with removable strips.
Cat # EK0530
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK0531
96 wells/kit, with removable strips.
Cat # EK0531
96 wells/kit, with removable strips.
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01437
100 μl
Cat # M01437
100 μl
Human, Mouse, Rat
ELISA
$480
Cat # EKC1688
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1688
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$405
Cat # A01437
100ul
Cat # A01437
100ul
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A01437-1
100 μg/vial
Cat # A01437-1
100 μg/vial
TNFRSF1B Overview
Facts about Tumor necrosis factor receptor superfamily member 1B.
Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B)
Receptor with higher affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2.
This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 cubes TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
Gene Information
| Human | |
|---|---|
| Gene Name: | TNFRSF1B |
| Uniprot: | P20333 |
| Entrez: | 7133 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
CD120b antigen; CD120b; Etanercept; p75 TNF receptor; p75TBPII; p75TNFR; soluble TNFR1B variant 1; TNF RII; TNFBRp80 TNF-alpha receptor; TNF-R2; TNFR2TNFR1B; TNF-R75; TNFR80; TNFRII; TNF-RII; TNF-R-II; TNFR-II; TNFRSF1B; tumor necrosis factor beta receptor; tumor necrosis factor binding protein 2; Tumor necrosis factor receptor 2; tumor necrosis factor receptor superfamily member 1B; tumor necrosis factor receptor superfamily, member 1B; Tumor necrosis factor receptor type II
Molecular Weight
Mass (kDA):
48.291 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p36.22 |
| Sequence: | 1; NC_000001.11 (12166948..12209222) |
Subcellular Localizations
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.; [Tumor necrosis factor-binding protein 2]: Secreted.
Diseases
- Inflammation
- Arthritis
- Rheumatoid Arthritis
- Malignant Neoplasms
- Inflammatory Response
- Dysequilibrium Syndrome
- Hypertensive Disease
- Neoplasms
- Insulin Resistance
- Autoimmune Diseases
- Autoimmune Reaction
- Familial Mediterranean Fever
Interacting Proteins
- GRN
- TNF
- TRAF2
Pathways
- Pathogenesis
- Inflammatory Response
- Immune Response
- Cell Death
- Angiogenesis
- Secretion
- Cytokine Production
- Osteoclast Differentiation
- Cell Proliferation
- Response To Drug
- Localization
- Cell Adhesion
- Cell Activation
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TNFRSF1B
bosterbio.com/bosterbio-gene-info-cards/TNFRSF1B
References
PMID: 2172983 by Kohno T., et al. A second tumor necrosis factor receptor gene product can shed a naturally occurring tumor necrosis factor inhibitor.
PMID: 2160731 by Smith C.A., et al. A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins.
2 Publications of Boster TNFRSF1B Antibodies & ELISA Kits
- PubMed ID: 27275821, Intravenous Administration Is an Effective and Safe Route for Cancer Gene Therap...
- PubMed ID: 24845203, Powerful inner/outer controlled multi-target magnetic nanoparticle drug carrier ...
*More publications can be found for each product on its corresponding product page