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- Table of Contents
TNFRSF25 Antibodies
AND TNFRSF25 ELISA kits, TNFRSF25 Proteins
Many biological assays use antibodies to detect TNFRSF25, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TNFRSF25 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TNFRSF25 antibodies...
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TNFRSF25 Infographic by Boster Bio
All TNFRSF25 Products
Product
Figures
Specificity
Applications
Price
Mouse
ELISA
$750
Cat # EK1515
96 wells/kit, with removable strips.
Cat # EK1515
96 wells/kit, with removable strips.
Human
ELISA
$750
Cat # EK1579
96 wells/kit, with removable strips.
Cat # EK1579
96 wells/kit, with removable strips.
Anti-DR3/Tnfrsf25 Antibody Picoband®
1 Citations
Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A03227-3
100 μg/vial
Cat # A03227-3
100 μg/vial
Human, Mouse, Rat
IF, ICC, WB
$370
Cat # M03227
100 μl/vial
Cat # M03227
100 μl/vial
TNFRSF25 Overview
Facts about Tumor necrosis factor receptor superfamily member 25.
Tumor necrosis factor receptor superfamily member 25 (TNFRSF25)
Receptor for TNFSF12/APO3L/TWEAK.
Interacts directly with the adapter TRADD.Mediates activation of NF-kappa-B and causes apoptosis. May play a role in regulating lymphocyte homeostasis.
Gene Information
| Human | |
|---|---|
| Gene Name: | TNFRSF25 |
| Uniprot: | Q93038 |
| Entrez: | 8718 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
APO3; Apo-3; Apoptosis-inducing receptor AIR; Apoptosis-mediating receptor DR3; Apoptosis-mediating receptor TRAMP; Death receptor 3; DR3; DR3member 12 (translocatingchain-association membrane protein); LARD; Lymphocyte-associated receptor of death; Protein WSL; Protein WSL-1; TNFRSF25; TRAMP; tumor necrosis factor receptor superfamily, member 25; WSL; WSL1; WSL-1
Molecular Weight
Mass (kDA):
45.385 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p36.31 |
| Sequence: | 1; NC_000001.11 (6460786..6466195, complement) |
Tissue Specificity
Abundantly expressed in thymocytes and lymphocytes. Detected in lymphocyte-rich tissues such as thymus, colon, intestine, and spleen. Also found in the prostate.
Subcellular Localizations
[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein.; [Isoform 9]: Cell membrane; Single-pass type I membrane protein.; [Isoform 11]: Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Secreted.; [Isoform 4]: Secreted.; [Isoform 5]: Secreted.; [Isoform 6]: Secreted.; [Isoform 7]: Secreted.; [Isoform 8]: Secreted.; [Isoform 10]: Secreted.; [Isoform 12]: Secreted.
Diseases
- Neoplasms
- Malignant Neoplasms
- Prostatic Neoplasms
- Malignant Neoplasm Of Prostate
- Inflammation
- Adenocarcinoma
- Carcinoma
- Neoplasm Metastasis
- Autoimmune Reaction
- Cell Transformation, Neoplastic
- Rheumatoid Arthritis
- Arthritis
- Carcinogenesis
Pathways
- Cell Death
- Cell Proliferation
- Secretion
- Pathogenesis
- Methylation
- Cell Cycle
- Angiogenesis
- Localization
- Dna Methylation
- Programmed Cell Death
- Induction Of Apoptosis
- Cytokine Production
- Cell Growth
PTMs
- Phosphorylation
- Cleavage
Research Areas
- Apoptosis
- Cell Biology
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TNFRSF25
bosterbio.com/bosterbio-gene-info-cards/TNFRSF25
References
PMID: 8934525 by Kitson J., et al. A death-domain-containing receptor that mediates apoptosis.
PMID: 8875942 by Chinnaiyan A.M., et al. Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95.