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- Table of Contents
Facts about Tryptophan 5-hydroxylase 1.
Human | |
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Gene Name: | TPH1 |
Uniprot: | P17752 |
Entrez: | 7166 |
Belongs to: |
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biopterin-dependent aromatic amino acid hydroxylase family |
EC 1.14.16; EC 1.14.16.4; indoleacetic acid-5-hydroxylase; L-tryptophan hydroxylase; MGC119994; TPH; TPH-1; TPRH; TRPH; tryptophan 5-hydroxylase 1; Tryptophan 5-monooxygenase 1; tryptophan hydroxylase (tryptophan 5-monooxygenase); Tryptophan Hydroxylase 1
Mass (kDA):
50.985 kDA
Human | |
---|---|
Location: | 11p15.1 |
Sequence: | 11; NC_000011.10 (18017555..18046269, complement) |
Isoform 2 seems to be less widely expressed than isoform 1.
If you're interested in learning more about Boster bio, please read this article. We will discuss the company’s history, product line, Custom services and BeNeLux deliveries. Read on to learn more about Boster Bio's TPh2 marker. Boster Bio was founded by a group of scientists in 2009. It has grown to become a global company with a broad product line. Here are three examples:
Boster Bio's TPh2 Anti-bodies are available for biological studies of the TPh2 marker. These antibodies can react with TPh2 protein in many samples and are available in monoclonal as well as polyclonal versions. Boster Bio used rabbit and mouse as model organisms to develop these antibodies.
The Picokine(tm) platform is a new generation of immunoassays that enhance sensitivity of ELISA to the picogram level. Picokine, an ELISA instrument that is highly sensitive, has been validated for use with a variety samples. Images and validation procedures available upon request. The Supervision polymer based secondary antibodies can save up to 30 minutes on IHC analysis The Picoband technology is powered by insights in immunogen design and technical support from BeNeLux distributor Sanbio.
TPh2 is the gene that encodes tryptophan, hydroxylase. It can be detected using antibodies, monoclonal or polyclonal. Boster Bio developed antibodies for the TPh2 gene using rabbit and mouse samples. Scientists can submit results to specific species or applications and receive product credit. Visit the Boster Bio website for more information.
Boster biologicals TPh2 is available in a variety applications. Picokine(tm), which can be used to increase its sensitivity, can be used to increase it up to picogram levels. The kits are validated for multiple applications and samples, and the validation images and procedure are available on request. Another option is Supervision, a polymer based secondary antibody that saves up to 30 min in immunohistochemistry. Picoband is highly receptive to immunogen design insights. It is supported by technical support from BeNeLux distributor Sanbio.
There are many uses of the TPh2 marker for biology. Most biological tests use antibodies that recognize TPh2 among many animal samples. Boster Bio has developed TPh2 antibodies against rabbit and mouse. It is not required to use the antibody for TPh2 studies in all animal species. Boster Bio provides custom services and BeNeLux shipping. Boster Bio also offers antibodies that can be used to identify other cellular markers such as phosphodiesterase or alpha-sepha.
Boster Bio's products include ELISA kits and research antibodies that recognize biomarkers in cancer, developmental biology, neurosciences, and inflammation. Its antibodies exhibit high sensitivities and a high affinity to the recombinant genes. The company offers its antibodies for sale through tebubio. These antibodies are compatible with Flow, ELISA and IHC.
TPh2 is an important marker in a variety of biological assays. Many assays employ antibodies to detect this protein. Monoclonal antibodies can be developed to detect TPh2 using a variety o animal samples. Boster Bio also makes TPh2 antibody for rabbit and mouse. These antibodies are highly specific, and allow for differentiation between the two forms.
There are many options for purchasing the Boster bio TPh2 antibody. The Bosterbio antibody is optimized IHC. It has been tested in immunohistochemistry and ELISA on a panel of 250 human tissue samples. The antibodies are also quantified against known amounts of recombinant proteins. They are also available through tebu-bio. Boster bio antibodies are made by combining immunogens from other companies.
PMID: 2377472 by Boulalard S., et al. Complete coding sequence of human tryptophan hydroxylase.
PMID: 7986090 by Tipper J.P., et al. Cloning and expression of rabbit and human brain tryptophan hydroxylase cDNA in Escherichia coli.