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- Table of Contents
TFPI Antibodies
AND TFPI ELISA kits, TFPI Proteins
Many biological assays use antibodies to detect TFPI, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TFPI in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TFPI antibodies...
Designing a Western blot for TFPI? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the TFPI Western Blot GuideTFPI Infographic by Boster Bio
All TFPI Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK0840
96 wells/kit, with removable strips.
Cat # EK0840
96 wells/kit, with removable strips.
Human, Mouse
Flow Cytometry, IHC, IHC-F, ICC, WB
$370
Cat # A03697-1
100 μg/vial
Cat # A03697-1
100 μg/vial
Mouse
ELISA
$499
Cat # FEK1355
96 wells/kit, with removable strips.
Cat # FEK1355
96 wells/kit, with removable strips.
Human, Rabbit
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01052-3
100 μg
Cat # M01052-3
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01052-5
100 μg
Cat # M01052-5
100 μg
Human, Mouse, Rabbit, Rat
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01052-4
100 μg
Cat # M01052-4
100 μg
TFPI Overview
Facts about Tissue factor pathway inhibitor.
Tissue factor pathway inhibitor (TFPI)
Inhibits factor X (X(a)) directly and, in a Xa-dependent manner, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It owns an antithrombotic action and also the capability to connect with lipoproteins in plasma.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | TFPI |
| Uniprot: | P10646 |
| Entrez: | 7035 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
convertin; EPI; EPITFPI1LACITFI; Extrinsic pathway inhibitor; LACI; Lipoprotein-associated coagulation inhibitor; TFPI; tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor); tissue factor pathway inhibitor
Molecular Weight
Mass (kDA):
35.015 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q32.1 |
| Sequence: | 2; NC_000002.12 (187464230..187554505, complement) |
Tissue Specificity
Mostly in endothelial cells.
Subcellular Localizations
[Isoform Alpha]: Secreted.; [Isoform Beta]: Microsome membrane; Lipid-anchor, GPI-anchor.
Diseases
- Thrombosis
- Blood Coagulation Disorders
- Thrombophilia
- Inflammation
- Hemorrhage
- Venous Thrombosis
- Neoplasms
- Malignant Neoplasms
- Systemic Infection
- Thrombus
- Von Willebrand Disease
- Disseminated Intravascular Coagulation
- Infarction
Pathways
- Coagulation
- Blood Coagulation
- Fibrinolysis
- Hemostasis
- Pathogenesis
- Angiogenesis
- Localization
- Secretion
- Cell Proliferation
- Platelet Activation
- Proteolysis
- Inflammatory Response
- Platelet Aggregation
PTMs
- Cleavage
- Phosphorylation
- Glycosylation
- Oxidation
- Gpi Anchoring
- Reduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TFPI
bosterbio.com/bosterbio-gene-info-cards/TFPI
References
PMID: 2452157 by Wun T.-C., et al. Cloning and characterization of a cDNA coding for the lipoprotein- associated coagulation inhibitor shows that it consists of three tandem Kunitz-type inhibitory domains.
PMID: 2781520 by Girard T.J., et al. Identification of the 1.4 kb and 4.0 kb messages for the lipoprotein associated coagulation inhibitor and expression of the encoded protein.
2 Publications of Boster TFPI Antibodies & ELISA Kits
- PubMed ID: 10.1371/journal.pone.0173991, The duplication mutation of Quebec platelet disorder dysregulates PLAU, but not ...
- PubMed ID: 22866126, Xu Y, Qin X, Zhou J, Tu Z, Bi X, Li W, Fan X, Zhang Y. Oncol Lett. 2011 Sep 1;2(...
*More publications can be found for each product on its corresponding product page