This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Toll-like receptor 8 Antibodies
AND TLR8 ELISA kits, Toll-like receptor 8 Proteins
Many biological assays use antibodies to detect Toll-like receptor 8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Toll-like receptor 8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Toll-like receptor 8 antibodies...
Designing a Western blot for Toll-like receptor 8? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the TLR8 Western Blot GuideDesigning an IHC experiment for Toll-like receptor 8? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the TLR8 IHC GuideTLR8 Infographic by Boster Bio
All TLR8 Products
Product
Figures
Specificity
Applications
Price
Functional Assay
$7280
Cat # RC1030
1 Vial, Each vial contains 2 ~ 3 x 10^6 cells in 1 ml of 90% FBS + 10% DMSO.
Cat # RC1030
1 Vial, Each vial contains 2 ~ 3 x 10^6 cells in 1 ml of 90% FBS + 10% DMSO.
TLR8 Overview
Facts about Toll-like receptor 8.
Toll-like receptor 8 (TLR8)
Key part of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to germs.
Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory reaction. .
Gene Information
| Human | |
|---|---|
| Gene Name: | TLR8 |
| Uniprot: | Q9NR97 |
| Entrez: | 51311 |
Family
| Belongs to: |
|---|
| Toll-like receptor family |
Alternative Names
CD288 antigen; CD288; MGC119599; MGC119600; TLR8; toll-like receptor 8
Molecular Weight
Mass (kDA):
119.828 kDA
Genomic Context
| Human | |
|---|---|
| Location: | Xp22.2 |
| Sequence: | X; NC_000023.11 (12906620..12923169) |
Tissue Specificity
Detected in brain, heart, lung, liver, placenta, in monocytes, and at lower levels in CD11c+ immature dendritic cells.
Subcellular Localizations
Membrane; Single-pass type I membrane protein.
Diseases
- Innate Immune Response
- Virus Diseases
- Inflammation
- Infective Disorder
- Malignant Neoplasms
- Neoplasms
- Autoimmune Reaction
- Autoimmune Diseases
- Hiv Infections
- Influenza
- Hepatitis
- Inflammatory Response
Pathways
- Immune Response
- Cytokine Production
- Secretion
- Pathogenesis
- Innate Immune Response
- Localization
- Cell Activation
- Inflammatory Response
- Cytokine Secretion
- Rna Interference
- Cell Proliferation
- Viral Replication
- Chemokine Production
PTMs
- Phosphorylation
- Methylation
- Phosphorothioation
- Ubiquitination
Research Areas
- Cytokine Research
- Immunology
- Innate Immunity
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TLR8
bosterbio.com/bosterbio-gene-info-cards/TLR8
References
PMID: 11022119 by Du X., et al. Three novel mammalian Toll-like receptors: gene structure, expression, and evolution.
PMID: 11022120 by Chuang T.-H., et al. Cloning and characterization of a sub-family of human Toll-like receptors: hTLR7, hTLR8 and hTLR9.
1 Publications of Boster Toll-like receptor 8 Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.cellbi.2008.04.023, Inhibition of lipopolysaccharide‐mediated rat alveolar macrophage activation i...
*More publications can be found for each product on its corresponding product page