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- Table of Contents
Designing a Western blot for TNFRSF17? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the TNFRSF17 Western Blot Guide
Facts about Tumor necrosis factor receptor superfamily member 17.
Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL.
Promotes B-cell survival and plays a role in the regulation of humoral immunity.Activates NF-kappa-B and JNK. .
| Human | |
|---|---|
| Gene Name: | TNFRSF17 |
| Uniprot: | Q02223 |
| Entrez: | 608 |

| Belongs to: |
|---|
| No superfamily |

B cell maturation antigen; B-cell maturation protein; BCMA; BCMAtumor necrosis factor receptor superfamily member 17; BCMB-cell maturation factor; CD269 antigen; CD269; TNFRSF13A; TNFRSF17; tumor necrosis factor receptor superfamily, member 17
Mass (kDA):
20.165 kDA

| Human | |
|---|---|
| Location: | 16p13.13 |
| Sequence: | 16; NC_000016.10 (11965210..11968068) |
Expressed in mature B-cells, but not in T- cells or monocytes.
Cell membrane; Single-pass type III membrane protein. Endomembrane system; Single-pass type III membrane protein. Perinuclear Golgi-like structures.




PMID: 1396583 by Laabi Y., et al. A new gene, BCM, on chromosome 16 is fused to the interleukin 2 gene by a t(4;16)(q26;p13) translocation in a malignant T cell lymphoma.
PMID: 8165126 by Laabi Y., et al. The BCMA gene, preferentially expressed during B lymphoid maturation, is bidirectionally transcribed.
*More publications can be found for each product on its corresponding product page