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- Table of Contents
TNFSF13B Antibodies
AND TNFSF13B ELISA kits, TNFSF13B Proteins
Many biological assays use antibodies to detect TNFSF13B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TNFSF13B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TNFSF13B antibodies...
Designing a Western blot for TNFSF13B? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the TNFSF13B Western Blot GuideTNFSF13B Infographic by Boster Bio
All TNFSF13B Products
Product
Figures
Specificity
Applications
Price
Human BAFF / TNFSF13B ELISA Kit PicoKine®
5 Citations
Human
ELISA
$399
Cat # EK0663
96 wells/kit, with removable strips.
Cat # EK0663
96 wells/kit, with removable strips.
Mouse BAFF ELISA Kit PicoKine®
3 Citations
Mouse
ELISA
$499
Cat # EK0664
96 wells/kit, with removable strips.
Cat # EK0664
96 wells/kit, with removable strips.
Human BAFF/TNFSF13B PicoKine® Quick ELISA Kit
1 Citations
Human
ELISA
$499
Cat # FEK0663
96 wells/kit, with removable strips.
Cat # FEK0663
96 wells/kit, with removable strips.
Anti-BAFF/TNFSF13B Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A01257
100 μg/vial
Cat # A01257
100 μg/vial
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01257-3
100 μg
Cat # M01257-3
100 μg
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01257-2
100 μg
Cat # M01257-2
100 μg
Human
Cell Culture
$77
Cat # PROTQ9Y275-6
5ug,20ug,100ug
Cat # PROTQ9Y275-6
5ug,20ug,100ug
Mouse
Cell Culture
$77
Cat # PROTQ9WU72
5ug,20ug,100ug
Cat # PROTQ9WU72
5ug,20ug,100ug
SDS-PAGE, Bioactivity
$300
Cat # PROTQ9Y275-5
Starting from 10ug
Cat # PROTQ9Y275-5
Starting from 10ug
TNFSF13B Overview
Facts about Tumor necrosis factor ligand superfamily member 13B.
Tumor necrosis factor ligand superfamily member 13B (TNFSF13B)
Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA.
TNFSF13/APRIL binds to the exact same 2 receptors.Collectively, they form a two ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of older B-cells and the B-cell response.
Gene Information
| Human | |
|---|---|
| Gene Name: | TNFSF13B |
| Uniprot: | Q9Y275 |
| Entrez: | 10673 |
Family
| Belongs to: |
|---|
| tumor necrosis factor family |
Alternative Names
ApoL related ligand TALL-1; B lymphocyte stimulator; BAFF; BAFFB-cell activating factor; B-cell-activating factor; BLyS; BLYSB-lymphocyte stimulator; CD257 antigen; CD257; Dendritic cell-derived TNF-like molecule; DTL; TALL1; TALL-1delta BAFF; TALL1Delta4 BAFF; THANK; TNF- and APOL-related leukocyte expressed ligand 1; TNF and ApoL-related leukocyte expressed ligand 1; TNF homolog that activates apoptosis; TNFSF13B; TNFSF20; tumor necrosis factor (ligand) superfamily, member 13b; tumor necrosis factor (ligand) superfamily, member 20; tumor necrosis factor ligand superfamily member 13B; tumor n
Molecular Weight
Mass (kDA):
31.223 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 13q33.3 |
| Sequence: | 13; NC_000013.11 (108268240..108308484) |
Tissue Specificity
Abundantly expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bone marrow, T- cells and dendritic cells. A lower expression seen in placenta, heart, lung, fetal liver, thymus, and pancreas. Isoform 2 is expressed in many myeloid cell lines.
Subcellular Localizations
Cell membrane; Single-pass type II membrane protein.; [Tumor necrosis factor ligand superfamily member 13b, soluble form]: Secreted.
Diseases
- Autoimmune Reaction
- Autoimmune Diseases
- Lupus Erythematosus, Systemic
- Autoimmunity
- Arthritis
- Rheumatoid Arthritis
- Malignant Neoplasms
- Sjogren's Syndrome
- Neoplasms
- Lymphoma
- Inflammation
- B-cell Lymphomas
- Malignant Paraganglionic Neoplasm
Interacting Proteins
- CSE1L
- KPNB1
- TNFRSF13B
Pathways
- Pathogenesis
- Cell Activation
- Cell Maturation
- Secretion
- B Cell Activation
- Cell Proliferation
- Cell Development
- B Cell Proliferation
- Immune Response
- B Cell Homeostasis
- Cell Growth
- Immunoglobulin Production
- T Cell Activation
PTMs
- Phosphorylation
- Cleavage
- Citrullination
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TNFSF13B
bosterbio.com/bosterbio-gene-info-cards/TNFSF13B
References
PMID: 10331498 by Shu H.-B., et al. TALL-1 is a novel member of the TNF family that is down-regulated by mitogens.
PMID: 10359578 by Schneider P., et al. BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth.
9 Publications of Boster TNFSF13B Antibodies & ELISA Kits
- PubMed ID: 10.3389/fimmu.2020.625630, B Cell–Activating Factor Promotes B Cell Survival in Ectopic Lymphoid Tissues ...
- PubMed ID: 10.1097/MBC.0000000000000144, B-cell-activating factor, a proliferation inducing ligand and co-stimulatory mol...
- PubMed ID: 10.1016/j.trim.2017.12.004, Pretransplant serum BAFF levels are associated with pretransplant HLA immunizati...
- PubMed ID: 10.1002/JLB.4HI1018-390R, Frontline Science: Mast cells regulate neutrophil homeostasis by influencing mac...
- PubMed ID: , AB0018 B cell disturbance in rheumatoid arthritis patients: comparative study ...
- PubMed ID: 30988562 , Prognostic Significance of Serum BAFF, APRIL, TACI and BCMA Levels in Chronic Ly...
- PubMed ID: 29277566 , Pretransplant serum BAFF levels are associated with pretransplant HLA immunizati...
- PubMed ID: 30111397, Expression of B-cell activating factor in acute lymphoblastic leukemia patients
- PubMed ID: 24911453, G??zmen S, Karapnar Th, T??fek??i O, Vergin C, Y??ksel F, Irken G, Oren H. Blood...
*More publications can be found for each product on its corresponding product page