TOM1-like protein 1 Antibodies

AND TOM1L1 ELISA kits, TOM1-like protein 1 Proteins

Many biological assays use antibodies to detect TOM1-like protein 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TOM1-like protein 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TOM1-like protein 1 antibodies...

We validate the specificity of these antibodies to TOM1-like protein 1 by testing them on tissues known to express TOM1L1 positively and negatively. Browse below to find the TOM1L1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for TOM1-like protein 1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the TOM1L1 IHC Guide

TOM1L1 Infographic by Boster Bio

All TOM1L1 Products

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Anti-TOM1L1 Antibody Picoband®

Western blot analysis of TOM1L1 using anti-TOM1L1 antibody (A07598-2)

IHC analysis of TOM1L1 using anti-TOM1L1 antibody (A07598-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, WB

$370
Cat # A07598-2
100 μg/vial

TOM1L1 (NM_005486) Human Over-expression Lysate

Human

$960
Cat # LS010040
20 µg, 100 µg

TOM1L1 Overview

Facts about TOM1-like protein 1.

TOM1L1 3D structure. Source: alphafold

TOM1-like protein 1 (TOM1L1)

Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated.

May promote FYN activation, possibly by disrupting intramolecular SH3-dependent interactions (By similarity). .

Gene Information

Human
Gene Name:	TOM1L1
Uniprot:	O75674
Entrez:	10040

Family

Belongs to:

TOM1 family

Alternative Names

OK/KNS-CL.3; Src-activating and signaling molecule protein; SRCASMSrc activating and signaling molecule; target of myb 1-like 1; target of myb1 (chicken) homolog-like 1; target of myb1 (chicken)-like 1; target of myb1-like 1; Target of Myb-like protein 1; TOM1-like protein 1

Molecular Weight

Mass (kDA):
52.989 kDA

Genomic Context


Human

Location:	17q22
Sequence:	17; NC_000017.11 (54900691..54961967)

Subcellular Localizations

Golgi apparatus, Golgi stack. Endosome membrane. Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side. A small proportion is membrane-associated.

Diseases

Neoplasms
Carcinoma
Malignant Neoplasms
Keratosis
Colorectal Cancer
Malignant Squamous Cell Neoplasm
Skin Neoplasms
Dermatologic Disorders
Basal Cell Carcinoma
Neoplasms, Experimental
Myeloid Leukemia, Chronic
Growth Acceleration

Carcinogenesis
Seborrheic Keratosis
Myeloid Leukemia
Pancreatic Neoplasm
Malignant Neoplasm Of Pancreas
Esophageal Neoplasms

Interacting Proteins

CLTC
EGFR
GRB2
TOLLIP
TOM1

VAV2

Pathways

Keratinocyte Differentiation
Cell Proliferation
Keratinocyte Proliferation
Endocytosis
Localization
Pathogenesis
Transport
Cellular Homeostasis
Dna Methylation
Immune Response
Cytokinesis

Methylation
Cellular Localization
Cell Differentiation
Regulation Of Cell Proliferation
Cell Growth

PTMs

Phosphorylation
Ubiquitination

Methylation
Ribosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TOM1L1

References

PMID: 10329004 by Seroussi E., et al. TOM1 genes map to human chromosome 22q13.1 and mouse chromosome 8C1 and encode proteins similar to the endosomal proteins HGS and STAM.