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- Table of Contents
Protein Wnt-2 Antibodies
AND WNT2 ELISA kits, Protein Wnt-2 Proteins
Many biological assays use antibodies to detect Protein Wnt-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein Wnt-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein Wnt-2 antibodies...
Designing a Western blot for Protein Wnt-2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the WNT2 Western Blot GuideWNT2 Infographic by Boster Bio
All WNT2 Products
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Specificity
Applications
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WNT2 Overview
Facts about Protein Wnt-2.
Protein Wnt-2 (WNT2)
Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that leads to activation of transcription factors of the TCF/LEF household (PubMed:20018874).
Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung growth.
Gene Information
| Human | |
|---|---|
| Gene Name: | WNT2 |
| Uniprot: | P09544 |
| Entrez: | 7472 |
Family
| Belongs to: |
|---|
| Wnt family |
Alternative Names
INT1L1; INT1L1secreted growth factor; Int-1-like protein 1; Int-1-related protein; IRP; IRPprotein Wnt-2; wingless-type MMTV integration site family member 2; Wnt2; Wnt-2
Molecular Weight
Mass (kDA):
40.418 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q31.2 |
| Sequence: | 7; NC_000007.14 (117275451..117323058, complement) |
Tissue Specificity
Expressed in brain in the thalamus, in fetal and adult lung and in placenta.
Subcellular Localizations
Secreted, extracellular space, extracellular matrix. Secreted.
Diseases
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Malignant Paraganglionic Neoplasm
- Malignant Neoplasm Of Stomach
- Cell Transformation, Neoplastic
- Autistic Disorder
- Carcinogenesis
- Stomach Neoplasms
- Neoplasm Metastasis
- Mammary Neoplasms
- Malignant Neoplasm Of Breast
Pathways
- Cell Proliferation
- Localization
- Pathogenesis
- Lung Development
- Glycosylation
- Cell Differentiation
- Cell Growth
- Regeneration
- Angiogenesis
- Methylation
- Cell Migration
- Lung Growth
- Cellular Senescence
PTMs
- Phosphorylation
- Glycosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/WNT2
bosterbio.com/bosterbio-gene-info-cards/WNT2
References
PMID: 2971536 by Wainwright B.J., et al. Isolation of a human gene with protein sequence similarity to human and murine int-1 and the Drosophila segment polarity mutant wingless.
PMID: 20018874 by Sousa K.M., et al. Wnt2 regulates progenitor proliferation in the developing ventral midbrain.
2 Publications of Boster Protein Wnt-2 Antibodies & ELISA Kits
- PubMed ID: 33359712, An R,Wang X,Yang L,Zhang J,Wang N,Xu F,Hou Y,Zhang H,Zhang L. Polystyrene microp...
- PubMed ID: 32463570, Xu T,Pan L,Li L,Hu S,Zhou H,Yang C,Yang J,Li H,Liu Y,Meng X,Li J.MicroRNA-708 mo...
*More publications can be found for each product on its corresponding product page