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- Table of Contents
XDH Antibodies
AND XDH ELISA kits, XDH Proteins
Many biological assays use antibodies to detect XDH, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with XDH in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop XDH antibodies...
Designing a Western blot for XDH? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the XDH Western Blot GuideDesigning an IHC experiment for XDH? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the XDH IHC GuideXDH Infographic by Boster Bio
All XDH Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A01884-2
100 µg/vial
Cat # A01884-2
100 µg/vial
Human, Mouse, Rat
Flow Cytometry, IHC, IHC-F, ICC, WB
$370
Cat # A01884
100 μg/vial
Cat # A01884
100 μg/vial
Anti-Xanthine Oxidase Rabbit Monoclonal Antibody
2 Citations
Human, Mouse, Rat
IHC, WB
$370
Cat # M01884-2
100 μl/vial
Cat # M01884-2
100 μl/vial
Human
$960
Cat # LS007498
20 µg, 100 µg
Cat # LS007498
20 µg, 100 µg
XDH Overview
Facts about Xanthine dehydrogenase/oxidase.
Xanthine dehydrogenase/oxidase (XDH)
Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine.
Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species.
Gene Information
| Human | |
|---|---|
| Gene Name: | XDH |
| Uniprot: | P47989 |
| Entrez: | 7498 |
Family
| Belongs to: |
|---|
| xanthine dehydrogenase family |
Alternative Names
EC 1.17.1.4; EC 1.7.2.2; xanthene dehydrogenase; xanthine dehydrogenase; xanthine dehydrogenase/oxidase; xanthine oxidase; xanthine oxidoreductase; XDHA; XO; XOR
Molecular Weight
Mass (kDA):
146.424 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2p23.1 |
| Sequence: | 2; NC_000002.12 (31334320..31414777, complement) |
Tissue Specificity
Detected in milk (at protein level).
Subcellular Localizations
Cytoplasm. Peroxisome. Secreted.
Diseases
- Ischemia
- Hypoxia
- Hereditary Xanthinuria
- Reperfusion Injury
- Neoplasms
- Hyperuricemia
- Inflammation
- Anoxia
- Malignant Neoplasms
- Gout
- Kidney Failure
- Kidney Diseases
- Nephrolithiasis
Pathways
- Fermentation
- Pathogenesis
- Excretion
- Transport
- Secretion
- Proteolysis
- Localization
- Cell Death
- Lactation
- Cell Differentiation
- Hypersensitivity
- Inflammatory Response
- Translation
PTMs
- Oxidation
- Hydroxylation
- Reduction
Research Areas
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/XDH
bosterbio.com/bosterbio-gene-info-cards/XDH
References
PMID: 8224915 by Ichida K., et al. Cloning of the cDNA encoding human xanthine dehydrogenase (oxidase): structural analysis of the protein and chromosomal location of the gene.
PMID: 8135849 by Xu P., et al. Molecular cloning, tissue expression of human xanthine dehydrogenase.
2 Publications of Boster XDH Antibodies & ELISA Kits
- PubMed ID: 10.1155/2016/1591803, Effect of Blueberry Anthocyanins Malvidin and Glycosides on the Antioxidant Prop...
- PubMed ID: 27034731, Effect of Blueberry Anthocyanins Malvidin and Glycosides on the Antioxidant Prop...
*More publications can be found for each product on its corresponding product page