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- Table of Contents
XRCC5 Antibodies
AND XRCC5 ELISA kits, XRCC5 Proteins
Many biological assays use antibodies to detect XRCC5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with XRCC5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop XRCC5 antibodies...
Designing a Western blot for XRCC5? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the XRCC5 Western Blot GuideDesigning an IHC experiment for XRCC5? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the XRCC5 IHC GuideXRCC5 Infographic by Boster Bio
All XRCC5 Products
Product
Figures
Specificity
Applications
Price
Anti-Ku80/XRCC5 Antibody Picoband®
1 Citations
Human, Mouse, Rat
Flow Cytometry, IF, IHC, IHC-F, ICC, WB
$370
Cat # PB9464
100 μg/vial
Cat # PB9464
100 μg/vial
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PA1641
100 μg/vial
Cat # PA1641
100 μg/vial
Human
ELISA
$540
Cat # EKC2051
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2051
1 kit, containing two 96-well plates and all necessary reagents
Human
ELISA
$480
Cat # EKC1335
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1335
1 kit, containing one 96-well plate and all necessary reagents
Human
ELISA
$480
Cat # EKC1611
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1611
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
WB
$370
Cat # M01277
100 μl/vial
Cat # M01277
100 μl/vial
XRCC5 Overview
Facts about X-ray repair cross-complementing protein 5.
X-ray repair cross-complementing protein 5 (XRCC5)
Single-stranded DNA-dependent ATP-dependent helicase.
The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner.It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6.
Gene Information
| Human | |
|---|---|
| Gene Name: | XRCC5 |
| Uniprot: | P13010 |
| Entrez: | 7520 |
Family
| Belongs to: |
|---|
| ku80 family |
Alternative Names
80kDa; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; CTC85; CTCBF; EC 3.6.4.-; FLJ39089; G22P2; KARP1; KARP-1; Ku80; Ku86 autoantigen related protein 1,86 kDa subunit of Ku antigen; Ku86; Ku86DNA repair protein XRCC5; KUB2; NFIV; Thyroid-lupus autoantigen; TLAA; X-ray repair complementing defective repair in Chinese hamster cells 5(double-strand-break rejoining)CTC box-binding factor 85 kDa subunit; X-ray repair complementing defective repair in Chinese hamster cells 5(double-strand-break rejoining; Ku autoantigen, 80kD); X-ray repair cross-complementing
Molecular Weight
Mass (kDA):
82.705 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q35 |
| Sequence: | 2; NC_000002.12 (216109348..216206293) |
Subcellular Localizations
Nucleus. Nucleus, nucleolus. Chromosome.
Diseases
- Neoplasms
- Malignant Neoplasms
- Autoimmune Reaction
- Severe Combined Immunodeficiency
- Carcinoma
- Lupus Erythematosus, Systemic
- Autoimmune Diseases
- Immunologic Deficiency Syndromes
- Genomic Instability
- Cell Transformation, Neoplastic
- Malignant Paraganglionic Neoplasm
- Ataxia Telangiectasia
- Chromosome Breakage
Interacting Proteins
- APLF
- COIL
- GOLPH3
- HOXB7
- HSPB1
- PPM1G
- PRKDC
- TPT1
- XRCC6
Pathways
- Dna Repair
- V(d)j Recombination
- Double-strand Break Repair
- Cell Cycle
- Localization
- Dna Replication
- Telomere Maintenance
- Cell Death
- Cell Proliferation
- Aging
- Senescence
- S Phase
- Hypersensitivity
PTMs
- Phosphorylation
- Cleavage
- Methylation
- Demethylation
- Acetylation
Research Areas
- Cancer
- Chromatin Research
- Core ESC-Like Genes
- DNA Double Strand Break Repair
- DNA Repair
- Non-homologous end-joining
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/XRCC5
bosterbio.com/bosterbio-gene-info-cards/XRCC5
References
PMID: 2760028 by Yaneva M., et al. cDNA-derived amino acid sequence of the 86-kDa subunit of the Ku antigen.
PMID: 2308937 by Mimori T., et al. Isolation and characterization of cDNA encoding the 80-kDa subunit protein of the human autoantigen Ku (p70/p80) recognized by autoantibodies from patients with scleroderma-polymyositis overlap syndrome.