XK-related protein 8 Antibodies

AND XKR8 ELISA kits, XK-related protein 8 Proteins

Many biological assays use antibodies to detect XK-related protein 8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with XK-related protein 8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop XK-related protein 8 antibodies...

We validate the specificity of these antibodies to XK-related protein 8 by testing them on tissues known to express XKR8 positively and negatively. Browse below to find the XKR8 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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XKR8 Infographic by Boster Bio

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Anti-XK-related protein 8 XKR8 Antibody

Western blot analysis of XKR8 in human stomach tissue lysate with XKR8 antibody at 1 μg/ml

Human

ELISA, IF, IHC-P, WB

$481
Cat # A12134
0.1 mg

XKR8 Overview

Facts about XK-related protein 8.

XKR8 3D structure. Source: alphafold

XK-related protein 8 (XKR8)

Promotes phosphatidylserine exposure on apoptotic cell surface, possibly by mediating phospholipid scrambling. Phosphatidylserine is a specific marker only present in the surface of apoptotic cells and acts as a specific signal for engulfment.

Has no impact on calcium-induced exposure of phosphatidylserine. Activated upon caspase cleavage, suggesting that it doesn't act prior the onset of apoptosis.

Gene Information

Human
Gene Name:	XKR8
Uniprot:	Q9H6D3
Entrez:	55113

Family

Belongs to:

XK family

Alternative Names

RP11-460I13.3; XKR8 XK, Kell blood group complex subunit-related family, member 8; XRG8

Molecular Weight

Mass (kDA):
44.655 kDA

Genomic Context


Human

Location:	1p35.3
Sequence:	1; NC_000001.11 (27959557..27968093)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/XKR8

References

PMID: 23845944 by Suzuki J., et al. Xk-Related protein 8 and CED-8 promote phosphatidylserine exposure in apoptotic cells.