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- Table of Contents
TFAP2A Antibodies
AND TFAP2A ELISA kits, TFAP2A Proteins
Many biological assays use antibodies to detect TFAP2A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TFAP2A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TFAP2A antibodies...
Designing a Western blot for TFAP2A? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the TFAP2A Western Blot GuideTFAP2A Infographic by Boster Bio
All TFAP2A Products
Product
Figures
Specificity
Applications
Price
Anti-AP2 alpha Rabbit Monoclonal Antibody
1 Citations
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01167
100 μl/vial
Cat # M01167
100 μl/vial
Human
$628
Cat # LS007020
20 µg, 100 µg
Cat # LS007020
20 µg, 100 µg
Human, Mouse, Rat
ELISA
$480
Cat # EKC1032
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1032
1 kit, containing one 96-well plate and all necessary reagents
TFAP2A Overview
Facts about Transcription factor AP-2-alpha.
Transcription factor AP-2-alpha (TFAP2A)
Sequence-specific DNA-binding protein which interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development.
They also suppress several genes such as MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle.
Gene Information
| Human | |
|---|---|
| Gene Name: | TFAP2A |
| Uniprot: | P05549 |
| Entrez: | 7020 |
Family
| Belongs to: |
|---|
| AP-2 family |
Alternative Names
Activating enhancer-binding protein 2-alpha; Activator protein 2; AP-2 transcription factor; AP2-alpha; AP2TFAP-2alpha; AP-2transcription factor AP-2 alpha (activating enhancer-binding protein 2 alpha); BOFS; FLJ51761; TFAP2; transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha); transcription factor AP-2-alpha
Molecular Weight
Mass (kDA):
48.062 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 6p24.3 |
| Sequence: | 6; NC_000006.12 (10396677..10420060, complement) |
Subcellular Localizations
Nucleus.
Diseases
- Malignant Neoplasms
- Neoplasms
- Crest Syndrome
- Malignant Neoplasm Of Breast
- Carcinoma
- Mammary Neoplasms
- Branchiooculofacial Syndrome
- Branchio-oto-renal Syndrome
- Malignant Paraganglionic Neoplasm
- Cleft Lip
- Cleft Palate
- Adenocarcinoma
- Congenital Abnormality
Interacting Proteins
- EP300
- GSTO2
- MAX
- MKRN3
- NPM1
- UBE2I
Pathways
- Localization
- Methylation
- Gastrulation
- Cell Proliferation
- Cell Differentiation
- Dna Methylation
- Cell Cycle
- Cell Growth
- Translation
- Cell Migration
- Histone Acetylation
- Oncogenesis
- Organ Development
PTMs
- Methylation
- Cleavage
Research Areas
- Cancer
- Transcription Factors and Regulators
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TFAP2A
bosterbio.com/bosterbio-gene-info-cards/TFAP2A
References
PMID: 3063603 by Williams T., et al. Cloning and expression of AP-2, a cell-type-specific transcription factor that activates inducible enhancer elements.
PMID: 8321221 by Buettner R., et al. An alternatively spliced mRNA from the AP-2 gene encodes a negative regulator of transcriptional activation by AP-2.
1 Publications of Boster TFAP2A Antibodies & ELISA Kits
- PubMed ID: 10.5650/jos.ess14009, Effects of Xanthohumol-Rich Hop Extract on the Differentiation of Preadipocytes
*More publications can be found for each product on its corresponding product page