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Product Info Summary
| SKU: | PROTP20809 |
|---|---|
| Size: | 2ug, 10ug, 1mg |
| Origin Species: | Human |
| Source: | Pichia pastoris |
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Product info
Product Name
IL-11 Interleukin-11 Human Recombinant Protein, Pichia
View all IL-11 recombinant proteins
SKU/Catalog Number
PROTP20809
Size
2ug, 10ug, 1mg
Description
IL11 Human Recombinant produced in Pichia Pastoris is a single, non-glycosylated, Polypeptide chain containing 177 amino acids (it differs from the 178 amino acid length of the native IL11 only in lack of the N-terminal praline residue) and having a molecular mass of 19kDa. The IL11 is purified by proprietary chromatographic techniques.
Storage & Handling
Lyophilized IL11 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL11 should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.
Cite This Product
IL-11 Interleukin-11 Human Recombinant Protein, Pichia (Boster Biological Technology, Pleasanton CA, USA, Catalog # PROTP20809)
Form
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
IL11 was Lyophilized from a 0.2 µm filtered concentrated solution of 20mM PB, pH7.2 and 2% Glycine buffer.
Purity
Greater than 95% as determined by SDS-PAGE.
Predicted MW
21.429kDa
Reconstitution
It is recommended to reconstitute the lyophilized Interleukin -11 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Amino Acid Sequence
The sequence of the first five N-terminal amino acids was determined and was found to be Gly-Pro-Pro-Pro-Gly.
Biological Activity
The ED50 as determined by the dose-dependent stimulation of the proliferation of murine 7TD1 was found to be less then 0.2ng-0.8ng/ml, corresponding to a Specific Activity of greater than 1,000,000 IU/ mg.
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Assay dilution & Images
Reconstitution
It is recommended to reconstitute the lyophilized Interleukin -11 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Validation Images & Assay Conditions
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Recombinant protein fun image
Protein Target Info & Infographic
Gene/Protein Information For IL11 (Source: Uniprot.org, NCBI)
Gene Name
IL11
Full Name
Interleukin-11
Weight
21.429kDa
Superfamily
IL-6 superfamily
Alternative Names
Adipogenesis inhibitory factor; AGIF; AGIFoprelvekin; IL11; IL-11; IL-11Oprelvekin; interleukin 11; interleukin-11; Oprelvekin IL11 AGIF, IL-11 interleukin 11 interleukin-11|adipogenesis inhibitory factor|oprelvekin
*If product is indicated to react with multiple species, protein information is based on the gene entry specified above in "Species".For more info on IL11, check out the IL11 Infographic
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In this infographic, you will see the following information for IL11: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us at [email protected].
Specific Publications For IL-11 Interleukin-11 Human Recombinant Protein, Pichia (PROTP20809)
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