Recombinant Mouse LIF Protein

LIF (leukemia inhibitory factor) is a widely expressed pleiotropic member of the IL-6 family of cytokines. The protein encoded by this gene is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Product Info Summary

SKU: R01400-1
Size: 100μg/vial
Origin Species: Mouse
Source: E. coli Ser24-Phe203

Product Name

Recombinant Mouse LIF Protein

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SKU/Catalog Number

R01400-1

Size

100μg/vial

Form

Lyophilized

Description

LIF (leukemia inhibitory factor) is a widely expressed pleiotropic member of the IL-6 family of cytokines. The protein encoded by this gene is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Storage & Handling

Lyophilized recombinant Mouse Leukemia Inhibitory Factor remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rmLIF remains stable up to 2 weeks at 4°C or up to 3 months at -20°C.

Cite This Product

Recombinant Mouse LIF Protein (Boster Biological Technology, Pleasanton CA, USA, Catalog # R01400-1)

Formulation

Reconstitute in ddH2O at 100 μg/mL.

Predicted MW

22.008kDa

Endotoxin

Less than 1 EU/μg of LIF as determined by LAL method.

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Validation Images & Assay Conditions

Gene/Protein Information For LIF (Source: Uniprot.Org, NCBI)

Uniprot ID

P15018

Gene ID

3976

Gene Name

LIF

Full Name

Leukemia inhibitory factor

Weight

22.008kDa

Superfamily

LIF/OSM family

Alternative Names

CDF; D Factor; DIA; differentiation inhibitory activity; differentiation stimulating factor; Differentiation-stimulating factor; Emfilermin; HILDA; HILDAcholinergic differentiation factor; leukemia inhibitory factor (cholinergic differentiation factor); leukemia inhibitory factor; LIF; Melanoma-derived LPL inhibitor; MLPLI LIF CDF, DIA, HILDA, MLPLI LIF interleukin 6 family cytokine leukemia inhibitory factor|D factor|cholinergic differentiation factor|differentiation inhibitory activity|differentiation-inducing factor|differentiation-stimulating factor|hepatocyte-stimulating factor III|human interleukin in DA cells|melanoma-derived LPL inhibitor

*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".

For more info on LIF, check out the LIF Infographic

LIF infographic

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In this infographic you will see the following information for LIF: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us [email protected]

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