Product Info Summary
SKU: | A04571-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-Alpha-1D adrenergic receptor ADRA1D Antibody
View all alpha-1D Adrenergic R/ADRA1D Antibodies
SKU/Catalog Number
A04571-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Alpha-1D adrenergic receptor ADRA1D Antibody catalog # A04571-1. Tested in WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Alpha-1D adrenergic receptor ADRA1D Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A04571-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human THC2
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A04571-1 is reactive to ADRA1D in Human
Applications
A04571-1 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
60.463kDa
Background of alpha-1D Adrenergic R/ADRA1D
Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at 'Ser-62' and 'Ser-67', respectively. ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A. Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity high. Following DNA damage, it is also involved in checkpoint recovery by being inhibited. Phosphorylates histone protein in vitro; however such activity is unsure in vivo. May be involved in megakaryocyte differentiation.
Ota T., Nat. Genet. 36:40-45(2004).
Deloukas P., Nature 429:375-381(2004).
Beausoleil S.A., Nat. Biotechnol. 24:1285-1292(2006).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For ADRA1D (Source: Uniprot.org, NCBI)
Gene Name
ADRA1D
Full Name
Alpha-1D adrenergic receptor
Weight
60.463kDa
Superfamily
G-protein coupled receptor 1 family
Alternative Names
a-1D AdrenergicR; ADRA1; ADRA1ADAR; ADRA1D; ADRA1R; adrenergic, alpha -1D-, receptor; adrenergic, alpha-1A-, receptor; adrenergic, alpha-1D-, receptor; ALPHA1; Alpha-1A adrenergic receptor; alpha-1D Adrenergic R; alpha-1D adrenergic receptor; alpha1D AdrenergicR; Alpha-1D adrenoceptor; Alpha-1D adrenoreceptor; alpha-1D-adrenergic receptor; Alpha-adrenergic receptor 1a; DAR; dJ779E11.2 ADRA1D ADRA1, ADRA1A, ADRA1R, ALPHA1, DAR, dJ779E11.2 adrenoceptor alpha 1D alpha-1D adrenergic receptor|adrenergic, alpha -1D-, receptor|adrenergic, alpha-1A-, receptor|alpha-1A adrenergic receptor|alpha-1D adrenoceptor|alpha-1D adrenoreceptor|alpha-adrenergic receptor 1a
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ADRA1D, check out the ADRA1D Infographic
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In this infographic, you will see the following information for ADRA1D: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Alpha-1D adrenergic receptor ADRA1D Antibody (A04571-1)
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No publications found for A04571-1
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