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Product Info Summary
| SKU: | A02929-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-Angiopoietin-related protein 3 ANGPTL3 Antibody
View all Angiopoietin-like Protein 3/ANGPTL3 Antibodies
SKU/Catalog Number
A02929-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Angiopoietin-related protein 3 ANGPTL3 Antibody (Catalog # A02929-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
ANGPTL3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-Angiopoietin-related protein 3 ANGPTL3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02929-1)
Host
Rabbit
Contents
ANGPTL3 antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
ANGPTL3 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human ANGPTL3. The immunogen is located within the last 50 amino acids of ANGPTL3.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
ANGPTL3 antibody is human, mouse and rat reactive. ANGPTL3 antibody is predicted not to cross-react with other ANGPTL family proteins.
Reactive Species
A02929-1 is reactive to ANGPTL3 in Human, Mouse, Rat
Applications
A02929-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
53.637kDa
Background of Angiopoietin-like Protein 3/ANGPTL3
The angiopoietin-related protein 3 (ANGPTL3) is a member of a family of secreted proteins that function in angiogenesis (1). ANGPTL3 is processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metablism, while the C-terminal chain may be involved in angiogenesis (2,3). Recent experiments have shown that a deficiency of ANGPTL3 is associated with increased insulin sensitivity, lipoprotein lipase activity, and decreased serum free fatty acids, suggesting that ANGPTL3 may also play a role in modulating glucose metabolism (4).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ANGPTL3 antibody can be used for detection of ANGPTL3 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry at 5 μg/mL. For Immunoflorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of ANGPTL3 in human heart tissue lysate with ANGPTL3 antibody at (A) 1 and (B) 2 μg/ml.
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Immunohistochemistry of ANGPTL3 in rat heart tissue with ANGPTL3 antibody at 5 μg/mL.
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Immunofluorescence of ANGPTL3 in rat heart tissue with ANGPTL3 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For ANGPTL3 (Source: Uniprot.org, NCBI)
Gene Name
ANGPTL3
Full Name
Angiopoietin-related protein 3
Weight
53.637kDa
Alternative Names
AGNPT5; Ang-5; angiopoietin 5; Angiopoietin-5; angiopoietin-like 3; Angiopoietin-like Protein 3; angiopoietin-related protein 3; ANGPT5angiopoietin-5; ANGPTL3; FHBL2 ANGPTL3 ANG-5, ANGPT5, ANL3, FHBL2 angiopoietin like 3 angiopoietin-related protein 3|angiopoietin 5
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ANGPTL3, check out the ANGPTL3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ANGPTL3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Angiopoietin-related protein 3 ANGPTL3 Antibody (A02929-1)
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No publications found for A02929-1
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