Product Info Summary
SKU: | A06508-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse |
Host: | Rabbit |
Application: | ELISA, WB |
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Product info
Product Name
Anti-Bcl-2-like protein 12 BCL2L12 Antibody
SKU/Catalog Number
A06508-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Bcl-2-like protein 12 BCL2L12 Antibody catalog # A06508-1. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Bcl-2-like protein 12 BCL2L12 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06508-1)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human BCL2L12
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A06508-1 is reactive to BCL2L12 in Human, Mouse
Applications
A06508-1 is guaranteed for ELISA, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
36.821kDa
Background of BCL2L12
This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants.
Scorilas A., Genomics 72:217-221(2001) [PubMed: 11401436].
Hillman R.T., Genome Biol. 5:R8.1-R8.16(2004) [PubMed: 14759258].
Olsen J.V., Cell 127:635-648(2006) [PubMed: 17081983].
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Reconsitution
Restore with deionized water (or equivalent) for reconstitution volume of 100 µL
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
ELISA 1:5000
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For BCL2L12 (Source: Uniprot.org, NCBI)
Gene Name
BCL2L12
Full Name
Bcl-2-like protein 12
Weight
36.821kDa
Superfamily
Bcl-2 family
Alternative Names
Bcl-2 related proline-rich protein; bcl2-L-12; BCL2-like 12 (proline rich); bcl-2-like protein 12; Bcl-2-related proline-rich protein; BPR; MGC120313; MGC120314; MGC120315 BCL2L12 BCL2 like 12 bcl-2-like protein 12|BCL2-like 12 (proline rich)|Bcl-2 related proline-rich protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on BCL2L12, check out the BCL2L12 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for BCL2L12: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Bcl-2-like protein 12 BCL2L12 Antibody (A06508-1)
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No publications found for A06508-1
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