Anti-CD94 KLRD1 Monoclonal Antibody

Product Name

Anti-CD94 KLRD1 Monoclonal Antibody

View all CD94 Antibodies

SKU/Catalog Number

A03257-1

Size

100μl

Form

Liquid

Description

Boster Bio Anti-CD94 KLRD1 Monoclonal Antibody catalog # A03257-1. Tested in Flow Cytometry, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-CD94 KLRD1 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03257-1)

Host

Mouse

Contents

Ascitic fluid containing 0.03% sodium azide.

Clonality

Monoclonal

Clone Number

1H1

Isotype

IgG

Immunogen

Purified recombinant fragment of human CD94 expressed in E. Coli.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A03257-1 is reactive to KLRD1 in Human

Applications

A03257-1 is guaranteed for Flow Cytometry, WB Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

20.513kDa

Background of CD94

Cullins assemble a potentially large number of ubiquitin ligases by binding to the RING protein ROC1 to catalyse polyubiquitination, as well as binding to various specificity factors to recruit substrates. Cullin 7 is a component of E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Cullin 7 seems to be involved proteosomal degradation of proteins involved in endothelial proliferation and/or differentiation. Cullin 7 is part of a SCF-like complex consisting of CUL7, RBX1, SKP1, FBXW8 and GLMN isoform 1. Cullin 7 interacts with a complex of SKP1 and FBXW8, but not with SKP1 alone.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000
FC, 1:200-1:400

Validation Images & Assay Conditions

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Flow cytometric (FCM) analysis of RAJI cells using CD94 Monoclonal antibody (green) and negative control (purple).

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Western Blot (WB) analysis using CD94 Monoclonal antibody against recombinant protein.

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ELISA analysis of CD94 antibody.

Gene/Protein Information For KLRD1 (Source: Uniprot.org, NCBI)

Alternative Names

CD94 antigen; CD94; CD94natural killer cells antigen CD94; Killer cell lectin-like receptor subfamily D member 1; killer cell lectin-like receptor subfamily D, member 1; KLRD1; KP43; NK cell receptor KLRD1 CD94 killer cell lectin like receptor D1 natural killer cells antigen CD94|CD94 antigen|KP43|NK cell receptor|killer cell lectin-like receptor subfamily D, member 1

For more info on KLRD1, check out the KLRD1 Infographic

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In this infographic, you will see the following information for KLRD1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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