Product Info Summary
SKU: | A03772 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IF, IHC, WB |
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Product info
Product Name
Anti-Cholesterol 24-hydroxylase CYP46A1 Antibody
SKU/Catalog Number
A03772
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Cholesterol 24-hydroxylase CYP46A1 Antibody catalog # A03772. Tested in WB,IHC,IF applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Cholesterol 24-hydroxylase CYP46A1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03772)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
The antiserum was produced against synthesized peptide derived from human VIPR2 at amino acid range 83-132
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A03772 is reactive to CYP46A1 in Human, Mouse, Rat
Applications
A03772 is guaranteed for IF, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
56.821kDa
Background of CYP46A1
Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca2+ mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer By similarity.
An S., FEBS Lett. 375:121-124(1995).
Xu Y., Genomics 35:397-402(1996).
King M.M., Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:2000
IHC: 1:50-1:100
IF: 1:50-1:100
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For CYP46A1 (Source: Uniprot.org, NCBI)
Gene Name
CYP46A1
Full Name
Cholesterol 24-hydroxylase
Weight
56.821kDa
Superfamily
cytochrome P450 family
Alternative Names
CH24H; cholesterol 24-hydroxylase; CYP46CP46; Cytochrome P450 46A1; cytochrome P450, family 46, subfamily A, polypeptide 1; cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase); EC 1.14.13.98 CYP46A1 CP46, CYP46 cytochrome P450 family 46 subfamily A member 1 cholesterol 24-hydroxylase|CH24H|cholesterol 24-monooxygenase|cholesterol 24S-hydroxylase|cytochrome P450 46A1|cytochrome P450, family 46, subfamily A, polypeptide 1|cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase)
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CYP46A1, check out the CYP46A1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CYP46A1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Cholesterol 24-hydroxylase CYP46A1 Antibody (A03772)
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No publications found for A03772
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