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Product Info Summary
| SKU: | A01331-1 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, IHC |
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Product info
Product Name
Anti-Citron Antibody
View all Citron Kinase Antibodies
SKU/Catalog Number
A01331-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Citron Antibody catalog # A01331-1. Tested in ELISA, IHC applications. This antibody reacts with Human, Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Citron Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01331-1)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Citron
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A01331-1 is reactive to CIT in Human, Mouse
Applications
A01331-1 is guaranteed for ELISA, IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
231.431kDa
Background of Citron Kinase
Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Plays an important role in the regulation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/MLC2.
Nagase T., DNA Res. 6:63-70(1999).
Scherer S.E., Nature 440:346-351(2006).
Gruneberg U., J. Cell Biol. 172:363-372(2006).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC 1:100-1:300
ELISA 1:40000
Validation Images & Assay Conditions
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Protein Target Info & Infographic
Gene/Protein Information For CIT (Source: Uniprot.org, NCBI)
Gene Name
CIT
Full Name
Citron Rho-interacting kinase
Weight
231.431kDa
Superfamily
protein kinase superfamily
Alternative Names
CITK; citron (rho-interacting, serine/threonine kinase 21); Citron Rho-Interacting Kinase; Citron Rho-Interacting Serine/Threonine Kinase; CRIK; KIAA0949; MCPH17; Rho-interacting Serine/Threonine kinase 21; serine/threonine kinase 21; Serine/threonine-protein kinase 21; STK21 CIT CITK, CRIK, MCPH17, STK21 citron rho-interacting serine/threonine kinase citron Rho-interacting kinase|citron (rho-interacting, serine/threonine kinase 21)|serine/threonine kinase 21|serine/threonine-protein kinase 21
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CIT, check out the CIT Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CIT: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Citron Antibody (A01331-1)
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No publications found for A01331-1
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