Product Info Summary
SKU: | M00064 |
---|---|
Size: | 100 μl |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | Flow Cytometry, IF, IHC, ICC, WB |
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Product info
Product Name
Anti-CLOCK Monoclonal Antibody
SKU/Catalog Number
M00064
Size
100 μl
Form
Liquid
Description
Boster Bio Anti-CLOCK Monoclonal Antibody catalog # M00064. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-CLOCK Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00064)
Host
Rabbit
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Clonality
Monoclonal
Clone Number
ACCH-3
Isotype
Rabbit IgG
Immunogen
A synthesized peptide derived from human CLOCK
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M00064 is reactive to CLOCK in Human, Mouse, Rat
Applications
M00064 is guaranteed for Flow Cytometry, IF, IHC, ICC, WB Boster Guarantee
Observed Molecular Weight
66 kDa
Calculated molecular weight
95.304kDa
Background of CLOCK
Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns (4,5) P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3) . PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Participates in cellular signaling in response to various growth factors.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Innovating Scientists Reward
If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.
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Assay dilution & Images
Reconsitution
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:1000-1:5000
IHC 1:50-1:200
ICC/IF 1:50-1:200
FC 1:50
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of CLOCK expression in 293T cell lysate.
Click image to see more details
Immunohistochemical analysis of paraffin-embedded human thyroid carcinoma, using CLOCK Antibody.
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Immunofluorescent analysis of HeLa cells, using CLOCK Antibody .
Protein Target Info & Infographic
Gene/Protein Information For CLOCK (Source: Uniprot.org, NCBI)
Gene Name
CLOCK
Full Name
Circadian locomoter output cycles protein kaput
Weight
95.304kDa
Alternative Names
BHLHE8; circadian locomoter output cycles protein kaput; Class E basic helix-loop-helix protein 8; clock (mouse) homolog; clock homolog (mouse); CLOCK; EC 2.3.1.48; hCLOCK; KAT13D; KIAA0334bHLHe8circadian locomoter output cycles kaput protein CLOCK KAT13D, bHLHe8 clock circadian regulator circadian locomoter output cycles protein kaput|circadian locomoter output cycles kaput protein|class E basic helix-loop-helix protein 8|clock homolog
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CLOCK, check out the CLOCK Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CLOCK: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CLOCK Monoclonal Antibody (M00064)
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No publications found for M00064
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Recommended Resources
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Customer Reviews
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