Anti-CREB-BP Antibody

CBP/KAT3A antibody

Boster Bio Anti-CREB-BP Antibody (Catalog # A00205). Tested in WB, IHC, IF applications. This antibody reacts with Human. Cited in 1 publication(s).

Product Info Summary

SKU: A00205
Size: 100 µl
Reactive Species: Human
Host: Rabbit
Application: IF, IHC, WB

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Product Name

Anti-CREB-BP Antibody

View all CBP/KAT3A Antibodies

SKU/Catalog Number

A00205

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-CREB-BP Antibody (Catalog # A00205). Tested in WB, IHC, IF applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-CREB-BP Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00205)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human CREB-BP.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A00205 is reactive to CREBBP in Human

Applications

A00205 is guaranteed for IF, IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

265.351kDa

Background of CBP/KAT3A

Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1 in the presence of EP300. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers.

Zoi Lygerou, Nucleic Acids Res., Feb 1994; 22: 5332 - 5340.
Karsten Grote, J. Biol. Chem., Dec 2004; 279: 55675 - 55681.
Kumi Nagamoto-Combs, J. Biol. Chem., Feb 1997; 272: 6051.
Stephen J. Elliman, Isaac, J. Biol. Chem., Jan 2006; 281: 16 -19

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500

Validation Images & Assay Conditions

Gene/Protein Information For CREBBP (Source: Uniprot.org, NCBI)

Gene Name

CREBBP

Full Name

CREB-binding protein

Weight

265.351kDa

Alternative Names

CBP; CBPRTS; CREB binding protein; CREB-binding protein; CREBBP; EC 2.3.1.48; KAT3A; RSTS; RTS; Rubinstein-Taybi syndrome CREBBP CBP, KAT3A, MKHK1, RSTS, RSTS1 CREB binding protein CREB-binding protein|histone lysine acetyltransferase CREBBP|protein-lysine acetyltransferase CREBBP

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CREBBP, check out the CREBBP Infographic

CREBBP infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CREBBP: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

A00205 has been cited in 1 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Role of CREB in vasoactive intestinal peptide-mediated wound healing in human bronchial epithelial cells

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1 Customer Q&As for Anti-CREB-BP Antibody

Question

What is the amino acid sequence of the epitope for A00205?

Verified customer

Asked: 2019-09-14

Answer

The immunogen sequence for the Anti-CREB-BP Antibody (A00205) is VGDTTGDTLEKFVEGL. (uniprot: Q92793)

Boster Scientific Support

Answered: 2019-09-17

Order DetailsPrice
A00205-100uL

100uL

$360

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*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$360.00

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